Endocrine Abstracts

G protein-coupled receptors (GPCRs) are the largest family of membrane receptors and major drug targets. They play a fundamental role in the endocrine system by mediating the effects of several hormones and neurotransmitters. Alterations of GPCR signalling, for instance due to genetic mutations, are responsible for a variety of endocrine diseases ranging from congenital hypothyroidism to Cushing’s syndrome. My group develops innovative optical methods such as fluorescenc...

Davide Calebiro is a Professor of Molecular Endocrinology and Wellcome Trust Senior Research Fellow at the Institute of Metabolism and Systems Research (IMSR) and the Centre of Membrane Proteins and Receptors (COMPARE) of the University of Birmingham.He leads a multidisciplinary research team comprising biologists, chemists, physicists, engineers and computer scientists focusing on the basic mechanisms of G protein-coupled receptor (GPCR) signalling and ...