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Endocrine Abstracts (2020) 70 AEP1090 | DOI: 10.1530/endoabs.70.AEP1090

1National and Kapodistrian University of Athens, Aretaieio Hospital, 2nd Department of Obstetrics and Gynecology, Athens, Greece; 2National and Kapodistrian University of Athens, Eginition Hospital, Women’s Mental Health Clinic, Department of Psychiatry, Athens, Greece; 3National and Kapodistrian University of Athens, First Department of Pediatrics and Chief Division of Endocrinology, Metabolism and Diabetes, Children’s Hospital Aghia Sophia, Athens, Greece


Introduction: The hypothalamic-pituitary-ovarian and/or adrenal axis as well as the autonomous nervous system affect significantly the intensity of menopausal symptoms Pre-existing levels of stress may affect the individual perception of menopausal symptoms. We aimed to evaluate the efficacy of a structured stress management program to reduce levels of stress and severity of climacteric symptoms, in a sample of middle-aged Greek women.

Methods: The sample consisted of 61 women with varying severity of climacteric symptoms, aged 40 up to 65 years, retrieved from the Menopause clinic of Aretaieio Hospital, National and Kapodistrian University of Athens, Greece. Women were randomized into the intervention group (N = 31) and the control group (N = 30). An 8-week stress management program was offered to the intervention group, which included structured sessions on healthy eating, daily exercise as well as teaching of self-awareness cognitive restructuring and relaxation techniques. We evaluated the following parameters both at baseline and after the completion of the program: 1) Climacteric symptoms (Green Climacteric Scale – GCS), 2) Mood status (Depression Anxiety Stress Scale, DASS); 3) Sleep quality (Pittsburg Sleep Quality Index, PSQI); 4) Self-esteem (Rosenberg Self-esteem Scale); 5) Health locus of control (HLC). Associations were evaluated using repeated-measure mixed-model ANOVA.

Results: We found significant time × group interaction with regards to: i) GCS-Psychological symptoms (F = 144.727; P < 0.001); ii) GCS-Vasomotor symptoms (F = 62.917; P < 0.001); iii) GCS-Physical symptoms (F = 41.233; P < 0.001); iv) PSQI-Subjective sleep quality (F = 27.094; P < 0.001); v) PSQI-Sleep latency (F = 10.424; P = 0.002); vi) PSQI-Sleep disturbance (F = 24.186; P < 0.001); vii) PSQI-Daytime dysfunction (F = 10.668; P = 0.002); viii) DASS-Depression (F = 13.249; P = 0.001); ix) DASS-Stress (F = 9.546; P = 0.003). Scores of vasomotor symptom severity, anxiety and depression were significantly lower at follow-up compared with baseline values, only in the intervention group.

Conclusion: An alternative non-pharmacological approach to the management of climacteric symptoms. Climacteric symptoms may be effectively managed with education on stress management techniques.

Volume 70

22nd European Congress of Endocrinology

Online
05 Sep 2020 - 09 Sep 2020

European Society of Endocrinology 

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