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Endocrine Abstracts (2020) 70 AEP407 | DOI: 10.1530/endoabs.70.AEP407

Hospital Charles Nicolle, Tunis, Tunisia


Introduction: Type 2 diabetes is a springboard to metabolic and cardiovascular complications. The objective of our work was to investigate the different cardiovascular risk factors in diabetic type 2 population, and study relation between the level of cardiovascular risk and the occurrence of degenerative complications.

Patients and Methods: Retrospective study including 149 patients with type 2 diabetes consultant at the Department of Endocrinology at the Charles Nicolle hospital.

Results: Our population showed a mean age of 59.3 ± 10.6 years, sex ratio of 58.3% and an average of 9.61 years of diabetes. The age was a risk factor in 67.79% of the population and family history of cardiovascular disease were present in 6.04%. Smoking was present in 53%, alcoholism in 8.7% and inactivity in 38.2% of the population. 30.87% of patients were on overweight and 33.56% were obese with android obesity in 69.3% and an average waist size of 99.4 cm ± 11.62. We found a low HDL cholesterol, hypertriglyceridemia and high LDL cholesterol in respectively 65.6%, 34.6% and 34.9% of the population. Hypertension was present in 64.4% of the population. For diabetic macrovascular complications (23.9% of the population) we found coronary artery disease (21.4%), a cerebrovascular accident (6.4%), arteritis of the lower limbs (26.8%) and limb amputation (11.4%). Micoangiopathic complications of diabetes were found in 70.4% of the population with retinopathy in 66.6% neuropathy in 43.3% and autonomic neuropathy in 15.4% of the population. Renal failure was present in 34% of the population with a mean creatinine 105.2 umol/l. The overall cardiovascular risk in patients was calculated according to the SCORE tool with a high risk (5% ≤ SCORE < 10%) in 4.7% and a very high risk (score ≥10%) in 95.3% of the population. Among the latter group microangiopathy complications were more frequent with 69.3% against only 28% for the first group.

Conclusion: The presence of cardiovascular risk factors increases the risk of occurrence of degenerative complications of diabetes. This justifies the need for a comprehensive care, targeting both diabetes and other cardiovascular risk factors in order to improve the profile of our diabetic patients.

Volume 70

22nd European Congress of Endocrinology

Online
05 Sep 2020 - 09 Sep 2020

European Society of Endocrinology 

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