Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2020) 70 AEP446 | DOI: 10.1530/endoabs.70.AEP446

ECE2020 Audio ePoster Presentations Diabetes, Obesity, Metabolism and Nutrition (285 abstracts)

Real-time continuous glucose monitoring impact on the metabolic control over the summer in children with type 1 diabetes

Simona Gabriela Duta 1 , Irina Bojoga 1,2 , Calapod Ioana Ruxandra 1 , Alexandra Marin 3 , Elisabeta Malinici 2,4 , Sorin Ioacara 2,4 & Simona Fica 1,2


1Spitalul Universitar de Urgență Elias, Endocrinology, București, Romania; 2Carol Davila University of Medicine and Pharmacy, București, Romania; 3C.I. Parhon National Institute of Endocrinology, Endocrinology, București, Romania; 4Spitalul Universitar de Urgență Elias, Diabetes, Bucharest, Romania


Background: Type 1 diabetes is a chronic disease requiring constant management and a disciplined lifestyle, especially in children. Real-time continuous glucose monitoring system (RT-CGMS) can be a useful tool in maintaining good glycemic control. In our medical centre, beginning with January 2019, a National Program for free distribution of RT-CGMS has been set in motion. The results from one of our previous studies indicated a significant increase in glycosylated haemoglobin (HbA1c) levels after 6 months from RT-CGMS initiation in children already on RT-CGMS at baseline, presumptuously due to a poor metabolic control during the summer months. The present study analyses this hypothesis.

Methods and materials: The analysis included 73 patients, aged under 18 upon entering the national program, who were divided into two groups, depending on the existence of a RT-CGMS at baseline: with previous RT-CGMS at baseline (RT-CGMS+) and without a RT-CGMS at baseline (RT-CGMS-). The baseline medical visit for these patients was done in June and July 2019 when they received free glucose monitoring sensors. The 3 months visit was considered at 90 ± 30 days from baseline. This is a unicentric, prospective cohort study.

Results: We evaluated 73 patients, 36 women (49.3%), mean age 11.2 ± 3.8 years (range: 2.3–17.8 years), mean diabetes duration 4.7 ± 3.1 years. The RT-CGMS + group has 26 subjects, mean age 11.1 ± 4.1 years, mean diabetes duration 5.4 ± 3.1 years, with a mean HbA1c 7.0 ± 0.5% (53 mmol/mol) at baseline. The RT-CGMS- group has 47 subjects, mean age 11.3 ± 3.6 years (P = 0.90 vs RT-CGMS+), diabetes duration 4.3 ± 3.1 years, and HbA1c 7.6 ± 1.1% (60 mmol/mol, P = 0,016 vs RT-CGMS+) at baseline. There was a significant increase in HbA1c after 90.2 ± 8.1 days in the RT-CGMS+ group reaching 7.5 ± 0.6% (58 mmol/mol, P < 0.01 vs baseline). The HbA1c variation did not change significantly in the RT-CGMS- group, with a value at 3 months of 7.8 ± 1.1% (62 mmol/mol, P = 0.075 vs baseline).

Conclusions: The results of the three months follow-up over the summer for the two patient groups indicated that RT-CGMS initiation in patients previously not exposed to RT-CGMS cancels the increase of HbA1c levels registered in patients previously exposed to RT-CGMS, who continue to use it for the same study period. This finding is consistent with the poor glycemic control observed during the summer in most patients, and especially in teenagers.

Volume 70

22nd European Congress of Endocrinology

Online
05 Sep 2020 - 09 Sep 2020

European Society of Endocrinology 

Browse other volumes

Article tools

My recent searches

No recent searches.