Endocrine Abstracts

Introduction: The vascular risk in type 1 diabetics appears to be secondary to the premature development of atherosclerosis.

The objective of this study was to determine the characteristics of the lipid profile of a type 1 diabetic population as well as the different factors that can influence these changes.

Methodology: It was a descriptive cross-sectional study including 30 type 1 diabetic patients, followed at the National Institute of Nutrition in Tunis. Patients underwent a careful clinical examination and a standard laboratory test.

Results: The average age of our population was 26.02 ± 7.90 years. The sex ratio was 1. The age of diabetes was 10.11 ± 5.16 years. The average HbA1c was 10.16 ± 2.1%. The lipid profile was characterized by: hypertriglyceridemia in 8 patients. Hypercholesterolemia in 19 patients. Hypo-HDLemia in 16 patients. We found macroangiopathic complications in 6 of our patients with coronary artery disease and lower limb arteritis; nephropathy, neuropathy and retinopathy microangiopathies were found in 11 patients. The analytical study found no correlation between microangiopathic or macroangiopathic complications and lipid abnormalities in our patients.

Conclusion: In accordance with data from the literature, our study reveals hypertriglyceridemia and hypo-HDLemia characterizing the lipid profile of type 1 diabetics. However, no correlation was found with the degenerative complications noted.