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Endocrine Abstracts (2020) 70 EP468 | DOI: 10.1530/endoabs.70.EP468

ECE2020 ePoster Presentations Thyroid (122 abstracts)

Etiological profile of hypothyroidism in Nepalese patients

Ansumali Joshi , Priyadarshini Yonzon & Sabeena Tamang


Kathmandu Diabetes and Thyroid Center, Kathmandu, Nepal


Background: Hypothyroidism is a common endocrine disorder. Common causes are autoimmune disease such as Hashimoto’ thyroiditis, surgical removal of the thyroid, drug induced and radioactive iodine (RAI) ablation.

Aim: The aim of our study was to determine the etiology of hypothyroidism in Nepalese patients.

Method: This is a retrospective study conducted in our opd from May 2015 to April 2019 in which data was collected from the patient record files of the subjects diagnosed with hypothyroidism. A total of 1000 patients with hypothyroidism were enrolled for this study.

Result: The findings of the study revealed that, out of 1000 hypothyroid patient, 83.2% were female and 16.8% were male. Among them 11.9% (n = 119) had a family history of hypothyroidism, 0.6% (n = 6) had undergone RAI Ablation and 0.4% (n = 4) had total thyroidectomy. 0.8% (n = 8) cases were congenital and out of them 0.7% (n = 7) had thyroid agenesis and 0.1% (n = 1) had ectopic thyroid (lingual thyroid). 50% (n = 500) cases were autoimmune with antiTPO antibody positivity. In 36.3%(n = 363), cause could not be determined.

Conclusion: The most common etiological diagnosis of hypothyroidism in Nepalese patients was autoimmune (Hashimoto’ thyroiditis). However, cause could not be determined in many patients.

Volume 70

22nd European Congress of Endocrinology

Online
05 Sep 2020 - 09 Sep 2020

European Society of Endocrinology 

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