Endocrine Abstracts

Background: Thyroid nodules are common with annual increasing trends worldwide. 5% to 15% of the thyroid nodules is thyroid cancer. The prevalence of thyroid nodule is 3%–7% prevalence by palpation and 19%–67% by high resolution ultrasound. Thyroid nodules are more prevalent in women and older age group. More than 95% of all thyroid nodules are benign.

Aim: The aim of this study is to assess the clinical profile of patients with solitary thyroid nodules in our center

Method: This is a retrospective study conducted in our opd in which data of patients with solitary thyroid nodules was collected from the patient record files. A total of 161 patients were enrolled for this study from April 2018 to April 2019.

Result: The findings of the study revealed that out of 161 patients, 82.20% were females and 16.56% were males, mean age was 47.27(±12) years, mean BMI was 26.85 (±5) kg/m². 94.4% were non-smokers and remaining 5.5% were smokers. 46.58% had right thyroid nodule and 50.93% had a left thyroid nodule and 2.48% had nodule in the isthmus. The largest dimension of thyroid nodule was 20.70(±12) mm. The cytological diagnosis distribution as per Bethesda nomenclature were 73.29% benign, 18% malignant (all Papillary Carcinoma), 5.59% non-Diagnostic or unsatisfactory and 1.2% suspicious for malignancy and 1.24% AUS (atypia of undetermined significance) or FLUS (follicular lesion of undetermined significance) respectively.

Conclusion: Prevalence of solitary thyroid nodules was significantly higher in females and obese.

Most of the nodules were benign. 18% solitary thyroid nodules were malignant and all were papillary carcinoma in our study.