Endocrine Abstracts

Introduction: Oral metastases are exceptional, representing about 1% of cancers of the oral region. The most common primary tumors are the lung in men and the breast in women. Thyroid carcinoma accounts for approximately 3% of all oral metastatic carcinomas.

We are reporting a case.

Observation: 65-year-old woman, followed for 35 years for a toxic large goiter at the expense of the right lobe under medical treatment, which consults following a bulky left mandibular mass. The scanner of the face finds an hypervascular tumor process of the lysing left masticatory space completely the rising branch of the mandible, the biopsy of which returns in favor of a secondary localization of papillary carcinoma of the thyroid TTF1 + TG +. The cervical ultrasound shows a voluminous right nodule classified EU-TIRADS III, the fine needle aspiration of which is an income in favor of papillary carcinoma. The extension report doesn’t find other locations. The patient benefits at one time from a total thyroidectomy and resection of the mandibular mass. The pathology study returns in favor of a vesicular thyroid carcinoma of 6.5 cm with mandibular metastasis classified PT3N0M1.

Discussion: Distant metastases from differentiated thyroid carcinomas are rare, the most common being the lung and bone (vertebrae, pelvis and ribs). Oral metastases are exceptional, affecting the mandible more often than the maxilla and are rather the plume of vesicular carcinomas due to hematogenous spread. These metastases cloud the prognosis with a 5-year survival rate of 40% and a 10-year survival rate of 27%.