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Endocrine Abstracts (2020) 70 EP527 | DOI: 10.1530/endoabs.70.EP527

ECE2020 ePoster Presentations Thyroid (122 abstracts)

Thyroid diseases and mastopathy

Irina Vasyhina 1 & Larisa Danilova 2


1The Republican Research Center for Radiation Medicine and Human Ecology, Endocrinology, Belarus; 2Belarusian Medical Academy for Postgraduate Education, Endocrinology, Belarus


Aim: To assess the thyroid and reproductive system status in 222 women with normal menstrual cycles.

Material and Methods: Patients were referred for thyroid ultrasonography and concurrent breast ultrasonography. The 160 women were divided into two groups, based on the nature of the thyroid pathology.

Results: The 1st group included 90 women with autoimmune thyroiditis (AIT), the median age was 36.00 [25.00; 50.00] years, the 2nd group – 70 women with nodular goiter, median age was 37.00 [31.00; 45.00] years. Women with AIT showed inverse significant correlations between age and testosterone level (ρ = –0.32; P < 0.001), age and DHEAS level (ρ = –0.38; P = 0.001), as well as BMI and FT4 (ρ = –0.24; P = 0.04). Direct significant correlations were established between progesterone and estradiol levels (ρ = 0.30; P = 0.01), progesterone and FT3 levels (ρ = 0.24; P = 0.04). Testosterone had a direct significant correlation with the FT3 level (ρ = 0.24; P = 0.04). DHEAS level had a direct significant correlation with the TSH level (ρ = 0.33; P = 0.004). Prolactin levels also had a direct significant correlation with estradiol levels (ρ = 0.23; P < 0.05). Age had a direct significant correlation with BMI (ρ = 0.50; P = 0.001). In the group of women with nodular goiter, age had an inverse significant correlation with progesterone levels (ρ = –0.37; P = 0.002); testosterone levels (ρ = –0.39; р = 0.002) and DHEAS levels (ρ = –0.47; P < 0.001). An inverse significant correlation was established between progesterone and FSH levels (ρ = –0.32; P = 0.01). In this group, a direct correlation was established between age and prolactin level (ρ = 0.31; P = 0.01) and BMI (ρ = 0.53; P < 0.001). The progesterone and testosterone levels had a direct significant correlation (ρ = 0.36; P = 0.004).

Conclusion: The obtained results indicate that the presence of thyroid pathology can be considered as one of the risk factors for the development of mastopathy.

Volume 70

22nd European Congress of Endocrinology

Online
05 Sep 2020 - 09 Sep 2020

European Society of Endocrinology 

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