ECE2020 ePoster Presentations Hot topics (including COVID-19) (57 abstracts)
Relationship between anxiety-depressive disorder and bone mineral density in diabetic patients with or without diabetic foot
Kader Ugur 1 , Tansel Ansal Balci 2 , Ahmet Karatas 3 , Umut Aydin 4 , Faruk Kılınç 1 , Suna Aydın 5 , Ramazan Fazıl Akkoç 6 , Fikri Selcuk Simsek 7 , Gamze Ayaz 4 & Vehbi Pehlivan 4
1Firat University, Elazig, Turkey., Department of Internal Medicine (Endocrinology and Metabolism Diseases), Faculty of Medicine,; 2Firat University, Elazig, Turkey., Department of Nuclear Medicine, Faculty of Medicine; 3Firat University, Elazig, Turkey., Department of Internal Medicine (Rheumatology) Faculty of Medicine; 4Firat University, Elazig, Turkey, Department of Internal Medicine, Faculty of Medicine; 5Fethi Sekin City Hospital, Health Science University, Elazig, Turkey., Cardiovascular Surgery Department,; 6Firat University, Elazig, Turkey., Department of Anatomy, Faculty of Medicine; 7Pamukkale University, Denizli, Turkey, Department of Nuclear Medicine, Faculty of Medicine
Purpose: Diabetes mellitus is a complicated disease that is associated with bone mineral density, depression, and anxiety in addition to its association with carbohydrate metabolism. The present study is intended to assess the biochemical measurements, depression and anxiety scores, and bone mineral densities (BMD) of diabetic patients with diabetic foot (DF) compared with those of diabetic patients without DF.
Materials and methods: A total of 37 patients diagnosed with DF and 40 non-DF diabetic patients who were admitted to the Fırat University Hospital Endocrinology and Metabolic Diseases Outpatient Clinic were included in this study according to their Hospital Anxiety Depression Score (HADS). Serum hemoglobin A1c (HbA1c), magnesium (Mg), albumin, urea, creatinine, calcium (Ca), phosphorus (P), parathyroid hormone (PTH), and vitamin D levels were measured along with body mass indexes (BMI). Patients with DF were also assessed according to Wagner’s classification. In addition, BMDs were measured from the lumbar and femoral head regions of the patients using dual X-ray absorptiometry.
Result: Depression and anxiety scores were significantly higher in female patients of both groups with and without DF, and the BMD value was also significantly lower in women than in men. Depression and anxiety scores increased as BMI increased in both groups but not to significant levels. BMD results were not significant but trended lower in the DF group. BMI and BMD were found to be positively correlated. Ca, P, and Mg levels related to bone metabolism were significantly lower in the DF group compared with those of the non-DF group.
Conclusion: According to the available data, anxiety, depression, and BMI increase as BMD decreases in DF patients, and this requires a multidisciplinary approach that integrates endocrine and metabolic treatment with psychiatric treatment for these patients.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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