Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2020) 70 EP562 | DOI: 10.1530/endoabs.70.EP562

ECE2020 ePoster Presentations Hot topics (including COVID-19) (57 abstracts)

A comparative evaluation of late effects of Orthodox religious fasting vs time restricted eating on metabolic profiles of overweight adults

Spyridon Karras 1 , Theocharis Koufakis 1 , Lilian Adamidou 2 , Maria Grammatiki 1 , Stergios Polyzos 3 , Paraskevi Karalazou 4 , Katerina Thisiadou 4 , Pantelis Zebekakis 1 , Kali Makedou 4 & Kalliopi Kotsa 1

1Division of Endocrinology and Metabolism, First Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece; 2Department of Dietetics and Nutrition, AHEPA University Hospital, Thessaloniki, Greece; 3First Laboratory of Pharmacology, School of Medicine, Aristotle University of Thessaloniki, Greece; 4Laboratory of Biological Chemistry, Medical School, Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece

Background: Previous research has demonstrated positive effects of Orthodox fasting (OF) and time restricted eating (TRE) on body weight (BW). However, little is known about the late, metabolic effects of the two diets.

Methods: 29 overweight adults followed a hypocaloric diet based on OF. A hypocaloric, TRE plan (eating between 08:00 to 16:00 h) was followed by 16 BW-matched participants. Anthropometric, glycemic and inflammation markers and serum lipids were assessed at baseline, at the end of the intervention (7 weeks) and 6 weeks after the cessation of diets (13 weeks).

Results: Both groups demonstrated a decrease in total energy intake at week 13, compared with baseline (OF: 1988 ± 339 vs 2124 ± 315 kcal, P < 0.001; TRE: 1960 ± 433 vs 2217 ± 350 kcal, P < 0.001). There was a trend of weight loss in both groups, which was evident at week 7 (TRE: –2.1 ± 1.0; OF: –2.0 ± 0.5 kg, P < 0.001 from baseline) and remained significant at week 13 (TRE: –2.9 ± 0.7; OF: –2.6 ± 0.3 kg, P < 0.001 from baseline). In the OF group, lipid concentrations decreased at week 7 and increased at week 13, compared with baseline. Neither group manifested differences in glycemic parameters.

Conclusions: These findings suggest that OF and TRE plans result in significant reductions in BW among overweight adults, which are sustainable even after the cessation of the diets. OF also promotes a decrease in plasma lipid concentrations, which is not evident 6 weeks after its end.

Volume 70

22nd European Congress of Endocrinology

05 Sep 2020 - 09 Sep 2020

European Society of Endocrinology 

Browse other volumes

Article tools

My recent searches

No recent searches.