ECE2021 Audio Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (223 abstracts)
Diabetes mellitus is associated with a higher relative risk for Parkinson’s disease in women than in men
Carola Deischinger 1 , Elma Dervic 2 , Michaela Kaleta 2 , Peter Klimek 2 & Alexandra Kautzky-Willer 1
1Medical University of Vienna, Endocrinology and MEtabolism, Vienna, Austria; 2Medical University of Vienna, Section for Science of Complex Systems, CeMSIIS, Vienna, Austria
Introduction
In general, the risk to develop Parkinson’s disease (PD) is higher in men compared to women. Besides male sex and genetics, research suggests diabetes mellitus (DM) is a risk factor for PD as well. In this population-level study, we aimed at investigating the sex-specific impact of DM on the risk of developing PD.
Research design and methods
Medical claims data were analyzed in a cross-sectional study in the Austrian population between 1997 and 2014. In the age group of 40–79 and 80 +, 235.268 patients (46.6% females, 53.4% males) with DM were extracted and compared to 767.681 non-diabetic controls (51.9% females, 48.1% males) in terms of risk of developing PD.
Results
Men with DM had a 1.46 times increased odds ratio (OR) to be diagnosed with PD compared to non-diabetic men (95% CI 1.38–1.54, P < 0.001). The association of DM with newly diagnosed PD was significantly greater in women (OR = 1.71, 95% CI 1.60–1.82, P < 0.001) resulting in a relative risk increase of 1.17 (95% CI 1.11–1.30) in the age group 40 to 79 years. In 80 +-year-olds the relative risk increase is 1.09 (95% CI 1.01–1.18).
Conclusions
Although men are more prone to develop PD, women see a higher risk increase in PD than men amongst DM patients.
Article tools
My recent searches
My recently viewed abstracts
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more