Endocrine Abstracts

BackgroundEpidemiological studies revealed up to 5-6 undiagnosed cases of type 2 diabetes mellitus (DM2) per 1 registered patient. The late diagnosis of DM2 presents a medical and socio-economic problem.The aim of the study to identify the most cost-effective, easy-to-use method for regular screening for DM2 in primary care settings in the Republic of Uzbekistan.Materials and methods4 d...

BackgroundObesity is an increasing public health problem all around the world. It plays role in the pathogenesis of many diseases, especially diabetes, hypertension, hyperlipidemia, cardiovascular diseases and cancer. The prevalence of weight-loss surgery is increasing as a result of developments of surgical techniques. In parallel with these developments, more patients admit for weight-loss surgery. Pharmacotherapy is one of the most important component...

IntroductionType 2 diabetes and hyperlipidemia are primarily managed with lifestyle modifications, self-monitoring of blood glucose, and medication. Patients who are obese and cannot achieve normal blood glucose levels despite diet, exercise, and multiple medications may be considered for bariatric surgery. Many diabetic patients with very high triglyceride levels are at high risk for ASCVD and therefore after triglyceride levels are con...

The control of obesity and the regulation of its components are strongly linked to nutrition. Thus, low calorie diets restricted in carbohydrates and lipids are becoming increasingly suitable for combating the complications of obesity. In the present work, we propose to report the short-term repercussions of dietary carbohydrate and lipid restriction on the weight parameters of the obese gerbil. Our experiment was undertaken on a species of gerbil (Gerbillus tarabuli) and last...

IntroductionType 1 diabetes mellitus (T1DM) is an autoimmune disease in which pancreatic βcells are destroyed, generating an incapacity to maintain appropriate insulin and glucose concentration. On the other hand, type 2 diabetes mellitus (T2DM) is associated with varying degrees of insulin resistance (IR) and relative insulin deficiency. The association of T1DM and the clinical features of T2DM as obesity, hypertension, dyslipidemia, or metabolic s...

IntroductionCarney complex (CNC) is an extremely rare genetic syndrome of pigmented skin lesions, endocrine hyper-function and myxoma. Given its diverse clinical manifestations, CNC is often misdiagnosed. Recognition of some special clinical manifestations and imaging features may help with the diagnosis. We report the case of CNC with endocrine and cutaneous tumors.CaseA 50 years old female patient followed ...

IntroductionPernicious anemia is an autoimmune cause of Vitamin B12 deficiency, that can occur as part of polyglandular adenopathy Type 3. According to one prospective serial study, it’s incidence was 2.3%in people ≥ 60 years of age, being more common in women than men. A case of polyglandular syndrome, most likely PGA-3, is being described. She had Type 1 diabetes, Hashimoto’s thyroiditis, vitiligo & pernicious anemia.<p class="a...

IntroductionWhile cervical lymph nodes are the region where head and neck malignancies frequently metastasize, prostate carcinoma rarely metastasizes to this area. Here, we will present a case with papillary thyroid microcarcinoma whose pathological lymph node cytology in the cervical region was found to be prostate carcinoma metastasis.Case <capti...

IntroductionIt is recommended to determine levothyroxine (LT4) dose individually in patients with hypothyroidism. However, higher doses of LT4 therapy are required to achieve target TSH levels in significant number of patients. Oral LT4 absorption occurs in the small intestine, especially in the jejunum and proximal ileum, while a small amount is absorbed in duodenum. Causes of LT4 malabsorption include helicobacter pylori infection, chronic atrophic gas...

BackgroundHypothyroidism is a common disorder in elderly. Management of elderly population requires special attention since both undertreatment and overtreatment leads to increased mortality and morbidity. Normal ranges of TSH differs as patients get older and it is recommended as 4-6 mIU/l in patients older than 70–80 years. In this study we aimed to evaluate the TSH concentrations of elderly patients (75 years of age and older) who are under levot...