Searchable abstracts of presentations at key conferences in endocrinology
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European Congress of Endocrinology 2021

22 May 2021 - 26 May 2021

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The European Congress of Endocrinology provides a global platform for the international endocrine community to discuss the latest advances in the field.

ea0073ep188 | Thyroid | ECE2021

ANCA vasculitis: a rare and serious complication of Benzylthiouracil

Ben Salah Raida , Kacem Faten Hadj , Imen Chabchoub , Frikha Faten , Abid Mohamed , Bahloul Zouhir

IntroductionVasculitis with antineutrophilic cytoplasmic antibodies (ANCA) has been reported in patients treated with anti-thyroid drugs, especially Propylthiouracil and exceptionally with benzylthiouracil (BTU). We present here a case of ANCA-anti-MPO-associated vasculitis related to BTU.Case presentationA 46 old women was treated with BTU during 18 months for Basedow’s...

ea0073ep189 | Thyroid | ECE2021

Papillary carcinoma arising in retrosternal ectopic thyroid tissue. A case report

Echchad Lamya , Khamal Doghri Sohaib , Rifai Kaoutar , Iraqi Hind , Mohamed El Hassan Gharbi

IntroductionEctopic thyroid tissue is a rare clinical entity, with a prevalence of 1: 300 000 in the general population. The ectopic tissue may be located anywhere from the base of the tongue to the diaphragm, the most frequent sites being lingual, thyroglossal, laryngotracheal, and lateral cervical regions. It may also occur in less frequent sites such as the esophagus, mediastinum, heart, adrenal glands, and pancreas. The mediastinum is the most freque...

ea0073ep190 | Thyroid | ECE2021

A case of primary hyperparathyroidism associated with papillary thyroid carcinoma

Bayar Ines , Tahri Soumaya , Ben Amor Bilel , Sayadi Hanene , Héla Marmouch , Inès Khochteli

IntroductionThe association between parathyroid and thyroid diseases is not uncommon; however concurrent presence of parathyroid adenoma and thyroid cancer is rare (1). As a natural consequence, preoperative imaging studies for diagnosis and localization of parathyroid adenomas may result with the detection of thyroid incidentalomas and most of these thyroid nodules should be evaluated by fine-needle aspiration biopsy before parathyroid surgery (1). We h...

ea0073ep191 | Thyroid | ECE2021

Place of surgery in Basedow’s disease ’About 100 cases’

Belkacem Samira

IntroductionGraves’ disease is an autoimmune thyroid disease manifested by hyperthyroidism, homogeneous goiter and sometimes ophthalmopathy. The frequency of the disease is less than 1% with a female predominance of 5–10/1 male. Its treatment is difficult because of the evolving vagaries of this disease. We report the results of surgery for Graves’ disease through a retrospective study.Material and methods<p clas...

ea0073ep192 | Thyroid | ECE2021

DeQuervain’s subacute thyroiditis

Kacem Faten Hadj , Ben Bnina Molka , Boujelben Kouloud , Elleuch Mouna , Ben Salah Dhouha , Charfi Nadia , Rekik Nabila , Mnif Mouna , Mnif Fatma , Abid Mohamed

IntroductionDeQuervain’s subacute thyroiditis (DST) is a rare pathology, defined by the involvement of the thyroid gland by an inflammatory process probably of viral origin, not suppurative and not autoimmune. In this context, we report 4 cases of TSD followed up in the endocrinology department over a period of 23 years, to highlight diagnostic and therapeutic particularities.ResultsThe average age was 3...

ea0073ep193 | Thyroid | ECE2021

Depression among patients with autoimmune thyroiditis

Roman Gimeno Sergio , Urdaniz Borque Rosana , Elena Pérez Galende , Borja Sanz Martín , Jose Jorge Ortez Toro

IntroductionToday, it is well recognized that disturbances in thyroid function may significantly affect mental status including emotion and cognition. Several studies have demonstrated the existence of a relationship between depression and hypothyroidism, although there is still no clear explanation of the pathophysiology that causes this association.ObjectivesTo assess whether there is a higher prevalence of...

ea0073ep194 | Thyroid | ECE2021

Problems in the diagnosis of thyroid orbitopathy

Volkova Natalya , Dzherieva Irina , Davidenko Ilya , Ganenko Lilia , Reshetnikov Igor , Sorokina Yulya , Zibarev Alexander , Degtyareva Yuliya , Gizatulina Gulnara , Koshkin Nikita

Thyroid orbitopathy (TO) is an autoimmune inflammatory disease of retroocular tissues. Mostly, TO is associated with Graves’ hyperthyroidism. The development of TO is accompanied by pathological changes in the soft tissues of the orbit with damage to the optic nerve and cornea, the accessory apparatus of the eye. Despite the presence of specific symptoms, the diagnosis of TO causes problems for doctors. A 61-year-old man complained of discomfort in the eyes, double vision...

ea0073ep195 | Thyroid | ECE2021

Prevalence of double vision (diplopia) and strabismus in patient with Graves’ orbitopathy

Boutzios Georgios , Koukoulioti Eleni , Karampela Athina , Chatzi Sofia , Giovannopoulos Ilias , Kouvelioti Sofia , Tzioufas Athanasios

IntroductionGraves’ disease (GD) is an autoimmune thyroiditis frequently associated with development of Graves’ orbitopathy (GO). Diplopia (double vision) is a major determinant of work disability in patients with GO. The aim of our study was to assess the prevalence of diplopia and strabismus in patients with GO.MethodsThis is a single-center observational study in an outpatient clinic of autoimmun...

ea0073ep196 | Thyroid | ECE2021

’Colloid leak’-An Phenomenon in thyroid surgery

Mayilvaganan Sabaretnam , Bhargav Panchangam Ramakanth , Idrees Sarrah

BackgroundThyroidectomy is the common most common endocrine surgical procedure varies from Scalpel to Robotic transoral thyroidectomy. Colloid nodules are common and easily operable without any difficulty. We report a phenomenon where in the surgery becomes difficult and lead to complications if not thought with this phenomenon – colloid leak.Material and methodThe endocrine surgeon (Associate Professor)...

ea0073ep197 | Thyroid | ECE2021

Transient thyrotoxicosis after laryngeal carcinoma surgery

Sofia Maria Lider Burciulescu , Costache Outas Mariana , Bunea Irina , Livia Gheorghiu Monica

IntroductionThyrotoxicosis debuted early after thyroid lobectomy is described in approximately 54% of cases. It has also been described in a few case reports after non thyroid neck surgeries or in invasive laryngeal cancer after total laryngectomy and debulking hemithyroidectomy.Case presentationPatient aged 53 years old, known with laryngeal carcinoma of 37/28/40 mm located at piriform sinus, linked by the l...

ea0073ep198 | Thyroid | ECE2021

Frequency and diagnostic value of Thyroid Autoantibodies

Urinbaeva Dinora , Salimova Mohina , Islomov Jasurbek , Ismailov Said , Shamansurova Zulaykho

IntroductionThyroid autoantibodies can detected in many disorders not only at the Hosimoto autoimmune thyroiditis. Their level and frequency may vary depending on many factors both thyroidal and nonthyroidal. Anti thyroid peroxidase autoantibodies (ATPO) is one of the well known among them. We analysed frequencies of higher level of ATPO among people with different types of thyroid diseases.Material and methods<p class="abstext...

ea0073ep199 | Thyroid | ECE2021

Unmasked Graves’ disease following tamoxifen withdrawal

El ArbI Kawthar , Safi Wajdi , Boujelben Khouloud , Mohamed Abdellahi Mohamed Ahmed , Mohamed Elmoctar Sidina , Mejdoub Nabila , Mnif Mouna , Kacem Faten Hadj , Mohamed Abid

IntroductionThe synthetic anti-oestrogen tamoxifen is the endocrine treatment modality most commonly used for therapy of hormone sensitive breastcancer. The influence of tamoxifen on thyroid function has not been fully elucidated.ObservationA 46-year-old female patient who presented a Graves’ disease diagnosed 10 years ago. She had a moderate vascular goiter and no ocular signs. She presented firstly a s...

ea0073ep200 | Thyroid | ECE2021

Graves’disease and breast cancer: Is there a link

El Arbi Kawthar , Safi Wajdi , Kacem Faten Hadj , Mohamed Elmoctar Sidina , Mohamed Abdellahi Mohamed Ahmed , Ben Salah Dhoha , Mejdoub Nabila , Mnif Mouna , Mohamed Abid

IntoductionThe link between hyperthyroidism and breast cancer has been the subject of much controversy and literature in the past. It poses a daily clinical problem of information and senological follow-up of thyroid patients. We report our patient’s case.ObservationA 46-year-old female patient who presented a Graves’ disease diagnosed 10 years ago. She had a moderate vascular goiter and no ocular s...

ea0073ep201 | Thyroid | ECE2021

Encapsulated follicular tumours of uncertain biological behaviour – clinicopathological and molecular analysis

Lukas Jindrich , Vorackova Alzbeta , Hintnausova Barbora , Sykorova Vlasta , Syrucek Martin , Duskova Jaroslava

BackgroundThe latest WHO classification of tumours of endocrine organs defines new units of borderline thyroid tumours (BTT) of uncertain biological behaviour. The aim of our study was to evaluate ultrasonographic, cytological features, mutation profile and surgery treatment in patients with these rare tumours.MethodsThe analysis of 8 out of 487 operated patients, who underwent thyroid surgery between June 20...

ea0073ep202 | Thyroid | ECE2021

Selpercatinib as an alternative therapy to Lenvatinib for metastatic medullary thyroid cancer. A case report.

Contreras Pascual Cristina , Montalban Mendez Cristina , Moreno Tirado Antonio , Maria Zhao Montero Benítez , Paloma González Lázaro , Julia Silva-Fernández , Florentino Del Val Zaballos , Francisco Javier Gómez Alfonso , Lomas Meneses Amparo , Inés Gómez García

Selpercatinib is a receptor tyrosine kinase RET inhibitor for the treatment of cancers such as RET-mutant medullary thyroid cancer, demonstrating partial response and low incidence of serious adverse events. Vandetanib, a tyrosine kinase inhibitor, has shown promising results with an increase in progression-free survival and prolonged lifetime, but it causes adverse events such as hypertension, diarrhea, rash, or long QT interval. Most of them are can be even disabling for the...

ea0073ep203 | Thyroid | ECE2021

A rare brain metastases of papillary thyroid cancer

Svilias Ioannis , Cap Jan , Gabalec Filip

IntroductionPapillary thyroid cancer (PTC) has generally good prognosis irrespective of lymph node metastases. The rate of survival in patients with distant metastases is variable, depending upon the site of metastases and radioiodine accumulation status. The median survival of patients with brain metastases is approximately one year.CaseWe present a 66 years old woman with a tumour triplicity (PTC, breast ca...

ea0073ep204 | Thyroid | ECE2021

Management of papillary thyroid microcarcinomas

Masmoudi Mohamed , Hasnaoui Mehdi , Wadii Thabet , Rim Hammemi , Khalifa Mighri

ObjectiveThe study’s purpose is to describe the therapeutic management of papillary thyroid microcarcinoma.Material and methodsThis is a retrospective study including 55 cases of papillary thyroid microcarcinoma treated at our department, from 2000 to 2020.ResultsOur study included 8 men and 47 women. The mean age was 48.64 years with extreme ages from 24 to ...

ea0073ep205 | Thyroid | ECE2021

Using TI-RADS classification increased accuracy of Thyroid cancer diagnosis

Salimova Mohina , Ismailov Said , Shamansurova Zulaykho

IntroductionProblems with thyroid cancer and its diagnosis are one of the current issues in modern endocrinology. Ultrasound examination detects thyroid nodules in 19-67%of the population, whereas the new classification of thyroid ultrasound examination proposed by the American Association of Thyroidologists – the use of TI-RADS in the diagnosis of thyroid cancer increases the diagnostic accuracy of this test by 91–95%. The aim of our study was...

ea0073ep206 | Thyroid | ECE2021

The impact of clinicopathological characteristics of differentiated thyroid cancer on free-disease survival

Charfi Hana , Fatma Hamza , Wiem Gherissi , Issam Jardak , Mohamed Maaloul , Faouzi Kallel , Wissam Amouri , Salma Charfeddine , Khalil Chtourou , Fadhel Guermazi

IntroductionDifferentiated thyroid cancer (DTC) is a rare disease (1%), and usually has good prognosis if well treated. However, the percentage of mortality due to this cancer is about 0.5%. Moreover, 5 to 27%of patients treated for DTC suffer from regional recurrence. Therefore, many research tried to identify predective factors for the survival, relapse and progression of this cancer.PurposeThe aim of our s...

ea0073ep207 | Thyroid | ECE2021

Patients with differentiated thyroid cancer treated with low iodine dose: clinical results

Redondo Enrique , Sara León Utrero , María Del Carmen Andreo-Lopez , Mª del Carmen Serrano Laguna , Hayon Ponce Maria , Maria Dolores Aviles Perez

Introduction and objectivesThyroid cancer treatment tends to be individualized based on risk stratification and increasingly less aggressive for low-risk tumors, as recent studies have shown that low doses of I-131 are just as effective than higher doses with excellent remission rates. The objective of our study was to evaluate the response after 1 year of treatment with 30 mCi of I-131 in patients with differentiated thyroid cancer.<p class="abstext...

ea0073ep208 | Thyroid | ECE2021

Lymph node metastasis in thyroid papillary microcarcinoma

Masmoudi Mohamed , Wadii Thabet , Chaima Zitouni , Arfi Taissir Ben , Hasnaoui Mehdi , Khalifa Mighri

IntroductionThyroid papillary carcinoma is the most common type of thyroid cancer. Thyroid papillary microcarcinoma is a subtype of papillary carcinoma that includes tumors with 10 mm or less diameter. As a result of diagnostic methods improvement, prevalence of this tumor is increasing. In this study, we reviewed lymph node metastasis characteristics among patients with papillary microcarcinoma.MethodsA retr...

ea0073ep209 | Thyroid | ECE2021

Differentiated thyroid carcinoma with metastatic presentation

Almeida Lucia , Almeida Ferreira Marta , Sousa Ana , Alves Helena , Ramalho Diogo , Correia Sara , Maria João Oliveira

IntroductionFollicular thyroid carcinoma (FTC) has metastasis in 10-15%; papillary thyroid carcinoma (PTC) rarely metastasizes. Bone metastasis are rare and can cause pain, fractures and spinal cord compression.Case-172 year-old male referred to the hospital with lower back pain. Imaging examination revealed lytic lumbar lesions. Thoracic-abdominal-pelvic-CT showed trachea compression by a multinodular right ...

ea0073ep210 | Thyroid | ECE2021

Epithelioid hemangioendothelioma with thyroid involvement – case report

Franco Sara , Cardoso Catarina , Correia Rafaela , Sequeira Mafalda , Dinis Sousa Magno , Filipa C. Bastos , Sequeira Pedro , Raquel Miranda Ana , Abecassis Francisca , Ana Gonçalves Ferreira , Barbosa David , Vara Luiz Henrique , Jorge da Cunha Oliveira

Epithelioid hemangioendotheliomas (EHE) are rare vascular tumors that are typically low to intermediate grade, but they can also have an aggressive behaviour. Mortality rate is dependent on the tumor location. It is frequently a solitary lesion located in the superficial or deep soft tissues, but they can be found in liver, lungs (normally multifocal), pleura, bones, lymph nodes and rarely in the thyroid gland. We describe a case of metastatic EHE with involvement of the thyro...

ea0073ep211 | Thyroid | ECE2021

Therapeutic and evolutive aspects of cardiothyreosis in adult population of southern tunisia

Elleuch Mouna , Ben teber Sawssan , Ben Salah Dhoha , Kacem Faten Hadj , Charfi Nadia , Mejdoub Nabila , Mnif Mouna , Mnif Fatma , Abid Mohamed

IntroductionCardiothyreosis is associated with higher morbidity and mortality than other forms of hyperthyroidism. The aim of our study was to identify its therapeutic and evolutive aspects in an adult population of southern Tunisia.MethodsRetrospective study including all cases of cardiothyreosis followed in our department during a period of 20 years.Results100 c...

ea0073ep212 | Thyroid | ECE2021

Ectopic thyroid tissue: about 2 cases

Sara Chtioui , Sanaa Bammou , Sanaa Rafi , Mghari Ghizlane El , Ansari Nawal El

IntroductionAccessory thyroid is defined as the presence of thyroid tissue in locations other than the normal anterior neck region between the second and fourth tracheal cartilages. It is a congenital disease caused by the abnormal migration of thyroid tissue in the embryonic stage. Lingual thyroid is the most common form of ectopic thyroid, extra lingual thyroid tissue is commonly located in the anterior cervical area, along the path of the thyroglossal...

ea0073ep213 | Thyroid | ECE2021

Coexistence of Hodgkin lymphoma and papillary thyroid carcinoma: 3 years follow up of a case report.

Bozkus Yusuf , Iyidir Ozlem , Feride Pınar Altay , Neslihan Başçıl Tütüncü

IntroductionThyroid cancers account for about 2.9%of all cancers. Although it is reported that the risk of developing PTC as the second primary cancer increases after treatment of Hodgkin lymphoma (HL), concomitant PTC and HL are quite rare and to the best of our knowledge we found only three cases in the literature. This case report presents the treatment management and three-year course of a male patient with simultaneous diagnosis of PTC and HL.<p...

ea0073ep214 | Thyroid | ECE2021

Disorders of carbohydrate metabolism in hyperthyroidism in children and adolescent

Muratova Shakhlo , Alimov Anvar

RelevanceExcess thyroid hormone as a result of thyroid hyperstimulation affects all types of metabolism, including carbohydrate metabolismPurposeTo assess the incidence of carbohydrate metabolism disorders in children and adolescents with hyperthyroidism.Materials and methodsHormonal analysis of thyroid status (TSH, free and total T3, free and total T4, TSHRAb, TP...

ea0073ep215 | Thyroid | ECE2021

A neck mass revealing thyroid hemiagenesis in an adolescent girl with euthyroidism.

Oueslati Ibtissem , Kardi Asma , Yazidi Meriem , Terzi Amani , Chaker Fatma , Chaker Melika

IntroductionThyroid hemiagenesis is defined as the absence of one lobe of the thyroid gland. It represents a rare congenital abnormality with a prevalence of 0.05 to 0.2%. The left lobe is more commonly affected than the right lobe. Thyroid hemiagenesis is incidentally found during a routine thyroid screen. Herein, we report a thyroid hemiagenesis revealed by a compensatory hypertrophy of the contralateral thyroid lobe in an adolescent girl with euthyroi...

ea0073ep216 | Thyroid | ECE2021

A case of Hashimoto’s thyroiditis following Graves’disease

Oueslati Ibtissem , Kardi Asma , Yazidi Meriem , Terzi Amani , Chaker Fatma , Chihaoui Melika

IntroductionGraves’ disease is typically characterized by the presence of circulating autoantibodies that stimulate the TSH receptor, inducing hyperthyroidism and goiter. Hashimoto’s thyroiditis is an autoimmune disease leading to thyroid tissue destruction by cell and antibody-mediated immune processes. The development of Hashimoto’s thyroiditis following Graves’ disease is rarely reported. Its pathogenesis is not confirmed. Herein, ...

ea0073ep217 | Thyroid | ECE2021

Thyroid dysfunction associated with immune checkpoint inhibitors therapy

Mazurina Natalya , Glibka Anastasiya , Troshina Ekaterina , Laktionov Konstantine , Kharkevich Galina , Sarantseva Kseniya , Kruteleva Svetlana

IntroductionProspective and retrospective trials report the incidence of endocrine adverse events provoked by immune checkpoint inhibitors (ICI) up to 30%. PD-1/PDL inhibitors have a higher incidence of thyroid dysfunction: hypothyroidism 5%-14%, transient hyperthyroidism – 3%-5%.The aim of the study was to assess thyroid function in PD-1/PDL treated patients.Materials and methods6...

ea0073ep218 | Thyroid | ECE2021

A rare case of Graves’ disease development from Hashimoto thyroiditis

Vainikonyte Kristapone Jelena , Samuiloviene Ernesta , Kuprionis Gintaras

The conversion of Hashimoto thyroiditis (HT) to hypothyroidism is frequently observed in daily clinical practice, but the development of Grave’s disease (GD) after long-standing hypothyroidism is rare and intriguing. A 70-year-old woman visited an endocrinologist, complaining of increased heart rate, anxiety, and a feeling of discomfort in the neck. Past medical history revealed HT with hypothyroidism. Laboratory tests showed significantly increased thyroid-stimulating ho...

ea0073ep219 | Thyroid | ECE2021

The influence of age-related androgen deficiency on risk factors for cardiovascular diseases in men with hypothyriodism

Krytskyy Taras

The long-term androgen deficiency (AD) in men with hypothyroidism is an important problem due to the fact that it leads to concomitant cardiac pathology, which remains the leading cause of mortality in the world. The presence of different points of view on the problem of AD and its effect on the risk factors for cardiovascular disease in patients with hypothyroidismattracts attention. The aim of the study is to assess the clinical signs of age-related androgen deficiency and t...

ea0073ep220 | Thyroid | ECE2021

Thyrotoxic periodic paralysis presenting in an adult male from Cambodia: a case report

Faïza Bensmaine , Gaelle Barrande , Paul Desaint , Alexis Jardin , Gaetan Plantefeve , Pierre Jean Guillausseau

IntroductionThyrotoxic periodic paralysis (TPP) is a rare complication of hyperthyroidism characterized by the sudden onset of hypokalemia and muscle paralysis. This rare but possible clinical presentation of thyrotoxicosis is significantly more predominant in males of asian descent. The mechanisms of hypokalemia are incompletely understood. The prevailing theories include increased Na-K ATPase pump activity and mutations in genes encoding Kir channels i...

ea0073ep221 | Thyroid | ECE2021

NIvolumab induced grade 3 hypothyroidism – case series

Cuneyt Bilginer Muhammet , Emur Gunay Yasemin , Tufekci Damla , Suat Demir Ahmet , Coskun Hulya , Nuhoglu Irfan , Ucuncu Ozge , Kocak Mustafa

IntroductionImmunological side effects related with use of immune checkpoint inhibitors (ICIs) are named as immune-related adverse events (irAEs). irAEs include clinical pictures such as autoimmune thyroiditis, hypophysitis, primary adrenal insufficiency and autoimmune diabetes mellitus. Nivolumab is an anti-PD-1 (anti-programmed cell death-1) monoclonal antibody approved for the treatment of malignant melanoma, advanced non-small cell lung cancer and ad...

ea0073ep222 | Thyroid | ECE2021

Difficulties in differential diagnosis of thyrotoxicosis: case report

Volkova Natalya , Dzherieva Irina , Davidenko Ilya , Degtyareva Yuliya , Ganenko Lilia , Zibarev Alexander , Reshetnikov Igor , Sorokina Yulya , Chernova Anastasia

Thyrotoxicosis (T) develops as a result of persistent excess of thyroid hormones (TH). There are two groups of diseases that are fundamentally different in pathogenesis. The first group includes those in which the production of TH increases. Diseases of the second group are accompanied by T caused by destruction of the thyroid gland tissue. Therapeutic approaches for different types of T are different, therefore, a careful differential diagnosis of T is necessary, even if at f...

ea0073ep223 | Thyroid | ECE2021

Prominent multinodular goiter in a patient with Williams-Beuren Syndrome

Maria del Pino Perez-Garcia , Esther Hernandez-Felipe , Paula Gonzalez-Diaz , Alba Lucia Tocino-Hernandez , Esperanza Perdomo-Herrera , Kuzior Agnieszka , Paula Maria Fernandez-Trujillo-Comenge , Alba Hernandez-Lazaro , Ricardo de Leon-Durango , Francisco Javier Martinez-Martin

ObjectivePresentation of multinodular goiter as an unusual feature in a patient with Williams-Beuren Syndrome.MethodsReview of the patient’s clinical records and of the relevant literature.IntroductionThe Williams-Beuren Syndrome is a multisystem disorder caused by a microdeletion of 1.5–1.8 megabase pairs on chromosome 7q11-123, with loss of 26–28 ...

ea0073ep224 | Thyroid | ECE2021

Acute myocaditis : a rare complication in the Graves disease

Laamouri Rihab , Aycha Ghachem , Rojbi Imen , Besrour Chayma , Lakhoua Youssef , Mchirgui Nadia , Ben Nacef Ibtissem , Khiari Karima

IntroductionGraves’ disease is an autoimmune disorder that has multiple cardiac repercussions including arrhythmias and heart failure. Acute myocarditis is a rarely described complication. In this context, we report a case illustrating this association.Case presentationA 23-year-old man has been followed for Graves’ disease that had been suspected by weight loss, tachycardia and bilateral and asymet...

ea0073ep225 | Thyroid | ECE2021

Pancytopenia in Grave’s disease: due to ATD or other autoimmune disease ?

Besrour Chayma , Rojbi Imen , Laamouri Rihab , Lakhoua Youssef , Mchirgui Nadia , Ben Nacef Ibtissem , Khiari Karima

IntroductionGrave’s disease is an autoimmune disease characterized by hyperthyroidism. It is in some cases associated to more autoimmune organs dysfunction. The antithyroid drugs are the first line treatement, and sometimes they are responsible for severe adverse effects.ObservationWe report the case of a 34 year-old man, treated for his grave’s disease with thiamazol for two years. Two weeks after ...

ea0073ep226 | Thyroid | ECE2021

Assessment of clinical burden and practice patterns in patients with chronic hypoparathyroidism in the United States (US): A claims data analysis using a surgery-based approach

Sharma Dolly , L Deering Kathleen , Loustau Patrick , Michael D. Culler , Allas Soraya , Weiss Blandine , Michelle Mitchell Deborah , Astolfi Danette , Mannstadt Michael

ObjectivesThere is a paucity of real-world studies on the clinical burden and practice patterns associated with chronic hypoparathyroidism (cHP). This study assesses the comorbidities, treatment and lab testing patterns in cHP patients identified using surgery-based criteria.MethodsThis was a retrospective study conducted using a large (130 million individuals) US claims database (HealthVerity Closed Payer Cl...

ea0073ep227 | Thyroid | ECE2021

Limitations for the use of ultrasound ablation of thyroid nodules

Aleksandrov Yuriy , Patrunov Yury

High-intensity focused ultrasound ablation (HIFU) was used in the treatment of thyroid nodules using the device “Echopulse” (Theraclion, France). The therapeutic sensor is represented by a piezoelectric lens with a diameter of 12 cm, with a variable radiation frequency from 0.8 to 1.6 MHz. The treatment was carried out automatically after preliminary planning. The impact zone (ablation focus) was marked automatically on the device screen. The limitations for using HI...

ea0073ep228 | Thyroid | ECE2021

Case report of a female patient with primary hyperparathyreoidism and acute pancreatitis

Martina Jambrović , Maja Mikolaj Kirić , Andreja Marić

A 65-year-old patient was hospitalized three times over a two-year period for severe acute pancreatitis. After the first hospitalization, cholecystectomy was performed. During the second hospitalization she was treated in the ICU because of the development of necrotizing emphysematous pancreatitis with the development of sepsis. During the third hospitalization the patient presents clinically with general weakness, agitation, visual hallucinations, disorientation and damaged c...

ea0073ep229 | Thyroid | ECE2021

Prifictive factors of malignancy in thyroid nodules: About 304 cases

Mouna Bellakhdar , Kdissa Amal , Monia Ghammam , Abdelkrim Asma Ben , Abir Meherzi , Wassim Kermani , Euch Koussay El , Mohamed Abdelkefi

BackgroundThe thyroid nodule is a common presentation. Its prevalence is estimated to be 5%. Surgical treatment could not be systematic. It requires structured diagnostic approach to ascertain the risk of malignancy and determine appropriate management.AimTo evaluate potential role of epidemiological, clinical and para clinical criteria as preoperative indcators of malignancy in thyroid nodules.<p class="...

ea0073ep230 | Thyroid | ECE2021

Exceptional thyroid cancer: a challenging diagnosis

Bellakhdher Mouna , Chouchane lobna , Ghammem Monia , Mestiri Sarra , Hasni Yosra , Meherzi Abir , Kermani Wassim , Mokni Moncef , El Ach Koussay , Zbdelkafi Mohamed

IntroductionThyroid carcinoma is the most common type of endocrine malignancy and the cancer with the largest annual increase in incidence in recent decades. They are classified as primary or metastatic. The most common thyroid cancer subtypes include papillary, follicular, medullary, and anaplastic. We aim to present 11 cases of exceptional thyroid malignancies managed in our department.Materiel and methodsA...