Endocrine Abstracts

IntroductionGynecomastia is the most common breast condition in men. The aim of our study is to describe clinical and therapeutic characteristics of patients with gynecomastia.MethodsA descriptive retrospective study was conducted in the department of endocrinology at the Hedi Chaker hospital, Sfax, Tunisia.ResultsWe collected the data of 28 patients with an avera...

IntroductionTriple-A syndrome (AS) is a rare autosomal recessive disorder, defined by the coexistence of primary adrenal insufficiency (PAI), alacrimia and achalasia cardia. The association to other endocrine has so far not been reported in the literature. Herein, we describe the coexistence of AS and congenital hypogonadotropic hypogonadism in two cases.Case presentation 1An 18-year-old patient, child of a c...

IntroductionMarfan syndrome is a rare autosomal dominant genetic disease resulting from a mutation in the gene encoding type 1 fibrillin (FBN1), which is a glycoprotein in the composition of elastic fibers in connective tissue. It mainly affects the cardiovascular, musculoskeletal and ocular systems.Case presentationWe report the case of a 14-year-old girl, with no particular history, referred to an endocrino...

8-year-old girl is referred to a Pediatric Endocrinologist for the appearance of thelarche, first noted at 6.5 years. She had a relevant clinical history of a neonatal meningitis, requiring prolonged hospitalization and the need for ventriculoperitoneal shunt. On physical examination, she had breast development and dark, coarse pubic hair compatible with Tanner stage 3. She weighed 32.3 kg (percentile – Pc- 75–90), her height was 128 cm (Pc 50) and her annual growth ...

IntroductionKleine-Levin syndrome, also called recurrent hypersomnia is a rare sleep disorder characterized by recurrent episodes of severe hypersomnia associated with cognitive and behavioral disturbances such as confusion, derealization, apathy, compulsive eating and hypersexuality. Menstrual-related hypersomnia is classified as a subtype of syndrome Levin-Kleine consisting of recurrent hypersomnia that is temporally linked with menses.<p class="ab...

ObjectiveTo determine the clinical, biological and etiological aspects of hirsutism.MaterialA retrospective study from 2009 to 2017 included 51 patients explored and followed for hirsutism in the endocrinology department of the Rabta hospital.ResultsThe mean age of hirsute patients was 29 years, their average age of menarche was 12 years old. Hirsutism appeared be...

Patients with polycystic ovary syndrome (PCOS) have features of the metabolic syndrome, including insulin resistance, obesity, and dyslipidemia, suggesting an increased risk for cardiovascular disease.ObjectiveTo assess the prevalence of metabolic syndrome in patients with a polycystic ovarian sydrome (PCOS).MaterialWe conducted a retrospective study including 51 patients with secondary...

Puberty, a crucial biological process, ends up in sexual maturation, reproductive capability and adult body size. It is controlled by hypothalamo–pituitary–gonadal axis (HPG), where hypothalamus synthesizes and secretes gonadotropin releasing hormone, which stimulates the adenohypophysis to produce follicle stimulating hormone (FSH) and luteinizing hormone (LH). FSH causes formation of sperms and LH stimulates production of testosterone (T). Puberty needs an intact H...

Introduction Preeclampsia (PE) accounts for approximately 2–5% of pregnancies, leading to several maternal-fetal complications. The present study aimed to review types of interventions affecting blood pressure and anxiety in women suffering from mild PE. Materials and methods This study was a narrative review based on keywords determined by the MeSH terms. For this purpose, the databases of PubMed, Scopus, Go...

IntroductionThe novel COVID-19 has been rapidly expanding and causing many deaths all over the world, since December 2019. The health condition and the coexistence of other diseases may affect the severity of SARS-CoV-2 infection.The state of the artPCOS is a common endocrine and metabolic disorder, afflicting females of reproductive age, with an incidence up to 10%. It is a heterogeneous clinical syndrome, c...

IntroductionGrowth retardation (GR) is a frequent complaint in pediatrics. A clear and rapid diagnostic process is essential in order to improve the prognosis for height. The aim of our study was to review the epidemiological, clinical and etiological aspects of GR and to assess the height gain particularly after treatment for Growth hormone (GH) deficiency.MethodologyThis is a retrospective study of 27 consu...

IntroductionXY testicular agenesis is a very rare disease. The phenotype of persons suffering is variable depending when the gonadic regression in utero occurs.ObservationWe have reported a 26 years old patient case, without particular history, monitored for puberty delay from the age of 17 years. The clinical examination reveals a very tall patient: 1m92, with macroskelia, a penis of normal size, a classifie...

IntroductionAlthough addressability for breast pathology is much lower in men than in women, the underlying causes of the initial complaints are often much more spectacular. Gynecomastia is one of the principal reasons for addressing the endocrinologist and next to the important psychosocial impact, sometimes it seems to be only the tip of the iceberg, revealing important underlying medical conditions.Case reports<p class="abst...