Endocrine Abstracts

Introduction

Diabetic peripheral neuropathy is a common degenerative complication of diabetes. The aim of our work is to focus on the prevalence of this complication in relation to the imbalance of diabetes in type 2 diabetics (T2DM).

Materials and methods

This is a retrospective study, including 202 type 2 diabetic patients hospitalized in an Endocrinology-Diabetology department, over a 6-year time period. All patients have benefited for a neurological examination with calculating of the DN4 score, the data were exploited by SPSS-V21.

Results

The mean age of our patients was 57.1 ± 13.1 years, with a sex ratio M/F of 0.25. The prevalence of diabetic neuropathy was 22.27% with an average duration of diabetes of 14.37 ± 8.85 years and an average HbA1c of 10.7 ± 1.6%. The DN4 score is positively correlated with the level of HbA1C (P = 0.04). Other microangiopathies were present in 53.33%, including nephropathy (24.44%) and retinopathy (35.55%). Macrovascular complications were present in 62.22%, including coronaropathy (42.22%), ischemic stroke (20%), peripheral arteriopathy (6.66%). The therapeutic management consisted of an optimal glycemic control, leading to an HbA1c level of 8.2 ± 2.2% on average after 3 months. 4.4% of patients were treated for neuropathic pain with an antidepressant.

Conclusion

The prevalence of diabetic neuropathy is high in T2DM, uncontrolled diabetes is the most common factor which is frequently associated with other degenerative complications. The preventive and curative treatment consists of an optimal glycemic control.