Endocrine Abstracts

A rare skeletal dysplasia-Progressive Pseudorheumatoid dysplasia—close mimicker of juvenile idiopathic arthritisIntroduction: Progressive pseudorheumatoid dysplasia (PPD) or spondyloepiphyseal dysplasia tarda with progressive arthropathy (SEDT-PA) is a rare autosomal recessive arthropathy of childhood involving the entire skeleton. Here we report first genetically proven case of PPRD from the country. Often mistaken as juvenile rheumatoid arthritis,...

Background: Childhood cancer survivors (CCS) are at high risk of 25-hydroxivitamin D (25(OH)D) inadequacy and the lack of a consensual definition has hampered its epidemiological study. Despite international recommendations, bone health and vitamin D inadequacy (VDI) are still quite undervalued, even in a high-risk population as CCS, due to disease treatment, physical limitations and insufficient solar exposure. Objectives: Our aims were to determine the...

Background: Metabolic bone disease of prematurity (MBDP) is characterized by decreased bone density as a result of insufficient mineral deposition in the bones of premature babies. Although the primary cause of MBDP is different from one case to another; either hypocalcaemia or hypophosphataemia, the main current practice is to treat it with phosphate supplements.Objectives: To emphasize the rule of parathyroid hormone and vitamin D investigations in MBD...