Endocrine Abstracts

Introduction: The management of childhood obesity is complex and requires intensive input from a multidisciplinary team. Pharmaceutical interventions may be required in addition to lifestyle modifications to treat morbid obesity. In a double blind randomised controlled trial, liraglutide, a glucagon-like peptide 1 (GLP-1) agonist along with dietary and lifestyle interventions showed beneficial BMI reduction in children and adolescents. We present a morbidly obese adolescent wi...

Introduction: The Tier 3 paediatric weight management service at University Hospital Southampton comprises a Paediatric Endocrine Consultant, a Clinical Nurse Specialist and Specialist Dieticians. Children may be referred if they have an endocrinopathy, metabolic co-morbidity or obesity syndrome. We offer at least two years of engagement within the service prior to discharge.Service Evaluation: Twenty-six Tier 3 patients were under follow-up between 1<su...

Background: Nearly 1 in 3 of UK children are overweight or have obesity. Obesity is associated with a higher risk of physical, psychological, and social ill-health yet doctors often do not initiate a conversation with parents about weight when a child has obesity. Studies have shown that doctors frequently fail to address childhood obesity with families in general paediatric outpatient clinics. Doctors report fear of upsetting parents. Parental views on this are largely unexpl...

Introduction: Resistant starch (RS) has beneficial effects on postprandial glucose metabolism in both animals and adults. Hitherto, it has not been studied in children. The long-term effects of RS in reducing obesity and improving metabolic profiles need to be investigated in children. Objectives: Our objective was to compare serial plasma glucose, insulin, gut hormone profiles and satiety scores in obese children after meals, containing increasing amoun...

Introduction: Obese adults of South Asian origin in the UK are considered to be obese at a BMI of 27.5 kg/M2 compared with 30 kg/m2 for other groups and are at increased risk of obesity related disorders such as type 2 diabetes. From July 2021, GPs have been offered financial incentives for referral of adults to weight management services. However no provision or adjustments have been made for children and young people especially those of South Asian orig...

Introduction: Raised intracranial pressure is a well-documented complication of obesity in the adult population, but this remains under-recognised in children and young people. The pathophysiology for this association remains unclear, but the complications of raised intracranial pressure can be devastating including potential visual loss. Therefore, the aim of our study was to investigate this link in children and young people.Method: Retrospective data ...

Introduction: Childhood obesity is a severe public health concern. Various complications are recognised in adults, but the data remains limited in the paediatric population. Therefore, the aim of this study is to investigate the complications observed in children and young people (CYP) with obesity.Method: Retrospective data collection from 125 CYP aged between 0 and 18 years with a body mass index (BMI) standard deviation score (SDS) of two or more abov...