Endocrine Abstracts

Introduction: Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is a newly defined entity accepted as a tumor precursor.

Objective of the study: To describ the epidemiological, clinical characteristics, and the evolutionary profile.

Methods: Retrospective study including 27 patients followed for noninvasive follicular thyroid neoplasm collected at the Endocrinology and Diabetology department of Ibn Rochd Casablanca University Hospital, spread from 2017 to 2021.

Results: The mean age of our patients was 51.3 years, with a clear predominance of women (88.8% of cases). The most frequent symptomatology was cervical swelling in 88.36%, the discovery was fortuitous in 11.63%. In our series 92% patients had multinodular goiter, 14.8% followed for dysthyroidism, 26.7% had no personal history and 2 patient had a familial history of thyroid carcinoma. All patients had clinical and biological euthyroidism except 3 patients who had hyperthyroidism. All patients underwent total thyroidectomy with noninvasive follicular tyroid neoplasm, the average size of 1.07 cm. Multifocality was objectified in 5 patients, without associated malignancy. Their was no indication for Lymph node dissection and Iratherapy (P=0.000), with no distant metastasis (P=0.000). The remission rate was objectified in 100%.

Conclusion: The diagnosis of NIFTP can only be made after complete resection of the lesion. Patients diagnosed with NIFTP without associated malignancy and without nodules detected can be spared from additional treatment and from the traditional follow-up recommended for differentiated thyroid cancer.