ECE2022 Eposter Presentations Late Breaking (59 abstracts)
Oncocytic carcinoma of the thyroid: Therapeutic and diagnostic challenge
Meherzi Abir , Marwa Ben Njima , Safa Jemli , Habiba Ben Sghaier , Mouna Bellakhdher , Jihene Houass , Kermani Wassim & Abdelkefi Mohamed
ENT Department Farhat Hached Hospital Sousse, Sousse, Tunisia
Background: To study the diagnostic difficulties, the clinical characteristics, as well as the therapeutic modalities of this entity.
Material and method: Report a case of oncocytic carcinoma of the thyroid of aggressive evolution collected in the ENT department and CCF Farhat Hached in Sousse.
Result: This is a 54-year-old patient, with no notable history, who was operated on in 2012 for a large goiter evolving for 3 years previously, having had a total thyroidectomy, with an anatomopathological examination objectifying an oncocytic adenoma on a goiter multi nodular. The patient was lost to follow-up, then reconsulted 5 years later, for the reappearance of a voluminous right anterior cervical swelling and cervical polyadenopathy, associated with dyspnea and hemoptysis. A cervico-thoracic CT showed a tumoral process above and below the glottic laryngeal with signs of locoregional extension, a tumoral process of the thyroid compartment and pulmonary lesions of secondary appearance. A histological re-reading was requested, correcting the diagnosis towards an oncocyte-type vesicular carcinoma. The patient had a lumpectomy with an anapath result confirming tumor recurrence. Additional radiation therapy was performed and the patient was put on L-thyroxine at a restraining dose. He was again lost sight.
Conclusion: Oncocytic carcinoma of the thyroid is a rare, aggressive tumor with metastatic potential posing an anatomopathologic diagnostic and therapeutic problem, requiring careful histological verification and adequate surgical management.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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