ECE2022 Eposter Presentations Calcium and Bone (114 abstracts)
A comparison of bone densitometry and mineral disorders in hemodialysis patients due to diabetics and non diabetics patients
Ramy Ben Tekaya 1 , Haifa Hachfi 1 , Mouna Brahem 1 , Zahra Sfar 1 , Olfa Jomaa 1 , Zohra Atii 2 & Mouhamed Younes 1
1University Hospital Tahar Sfar, Rheumatology Department, Mahdia, Tunisia; 2University Hospital Tahar Sfar, Nephrology Department, Mahdia, Tunisia
Introduction: The chronic kidney disease (CKD) is associated to various bone and mineral disorders.Many studies showed that diabetics influence the bone and mineral metabolism
Aim: To investigate the bone disorder in CKD and the effect of diabetes on bone mineral density.
Methods: This is a cross sectional study conducted in rheumatology department of Taher Sfar university hospital in mahdia, Tunisia. The study involved 61 patients with chronic hemodialysis. They were invited to participate and were included after signing informed consent until the calculated sample size was reached. Patients were asked to undergo a hip and lumbar (L2-L4) densitometry by DXA to measure bone mineral density (BMD).
Results: The studied group of 61 patients was 26 females (42,6%) and 35 males (57.4%), there mean age was 53.9 [17-83] years, with mean dialysis duration 6,1 years. The mean onset age of hemodialysis therapy was 44.7+/- 15.4 years. It was diabetic nephropathy in 25 cases (41%) vascular nephropathy in 15 cases and tubulointerstitial nephropathy in 21 cases (34,4). 23 patients (37,7%) had osteoporosis using the WHO criteria (T-score < -2,5), 26 patients (42,6%) had osteopenia and 12 patients had normal BMD. The mean bone mineral density of lumbar in diabetics patients and non-diabetics patients -1,72 vs -1,43 (P<0,005). The mean bone mineral density of the hip in diabetics patients and non-diabetics patients -1,83 vs -1,21 (P<0,005).
Conclusion: Our study showed that chronic kidney disease has an important impact on bone and mineral metabolism. Second our study showed that diabetes can worsen patient bone mineral density.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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