Endocrine Abstracts

Introduction: Primary hyperparathyroidism is a common pathology. The association of papillary thyroid carcinoma and primary hyperparathyroidism has been reported in 2.3–4.3% of patients operated on for primary hyperparathyroidism.We report the case of a patient with papillary thyroid carcinoma revealed by primary hyperparathyroidism

Observation: 53-year-old patient admitted for management of primary hyperparathyroidism. A cervical ultrasound revealed a right subthyroid tissue nodule suggestive of a parathyroid adenoma associated with a multiheteronodular goiter classified as eutirads 3-5. The cervical scan shows 2 lobar nodules, upper and lower right. Thyroid scintigraphy confirmed the upper and lower right parathyroid originthe patient benefited from an upper and lower adenomectomy + total thyroidectomy.The anatomopathological study was in favor of a parathyroid adenoma associated with a papillary thyroid carcinoma

Discussion &Conclusion: The coexistence of papillary thyroid carcinoma and hyperparathyroidism is thought to be rare. The mechanisms underlying this association have not been established. A possible hypothesis is suggested for this relationship based on shared embryological origin and genes, high parathyroid hormone, low 1,25 hydroxy vitamin D, hypercalcemia resulting in high levels of angiogenic growth factors.The presence of these two diseases can complicate patient management due to untreated hypercalcemia, unrecognized thyroid cancer and need for second surgery if not screened for both diseases carefully