Endocrine Abstracts

Introduction and Objectives: Poor metabolic control in Type 1 Diabetes Mellitus (DM 1) is associated with micro and macrovascular complications. The implementation of interstitial glucose monitoring systems has contributed to improving glycemic control in recent years. Our objective was to know the metabolic control in people with type 1 DM and the Flash system and to establish if there is an association between its use and glycemic control variables.

Material and Methods: Cross-sectional observational study in people with DM 1, carriers of Flash glucose monitoring system, with follow-up in a Regional Hospital (Hospital Santa Ana, Motril-Granada). Downloads were performed for the previous three months and glycemic control variables were analyzed: average glucose (mg/dl), % of time in range (TIR, 70-180 mg/dl), % above target (>180 mg/dl), % below target (<70 mg/dl), % coefficient of variation, estimated glycosylated hemoglobin (GMI, %) and low glucose events (in no.). Statistical analysis was performed using the SPSS 15.0 program.

Results: 179 patients were included, 51.9% women, with a mean age of 42.04±15.3 years. All patients were receiving basal-bolus insulin therapy. The average glucose of the last three months was 176.65±44.54 mg/dl and the estimated GMI was 7.4±0.84%. The mean number of readings per day was 9.25±6.4. The coefficient of variation was 37.7±8.8%. The mean time within target was 53.28±19.08%, over range was 41.8±20.8% and under range was 4.9±5.4%. Taking 10 or more readings per day was statistically significantly associated with lower mean glucose levels (164.0 vs 184.6, p<0.01), lower estimated GMI (7.23 vs 7.55, p<0.01), increased time in range (59.10 vs 49.60, p<0.01) and decreased time above target (35.06 vs 45.72, p<0.01).

Conclusions: Insufficient metabolic control was observed in people with DM 1 under follow-up in a Regional Hospital. 10 or more daily readings was associated with better results in terms of glucometry. Therefore, we could recommend the active and frequent use of the FLASH sensor in people with DM 1 to achieve better metabolic control.