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Endocrine Abstracts (2022) 81 EP349 | DOI: 10.1530/endoabs.81.EP349

1National Institute of Nutrition, Tunisia; 2Faculty of Medicine Of Tunis, Tunisia; 3University of Tunis El Manar, Tunisia


Introduction: Diabetes mellitus (DM) is the most common endocrine disorder. The skin manifestations of diabetes can vary depending on the duration of the disease and the control of blood glucose levels. Almost all patients with DM eventually develop skin changes due to the long-term effects of hyperglycemia on microcirculation and skin collagen. This study was conducted to find the hospital based prevalence of mucocutaneous manifestations in patients with diabetes mellitus, their clinical pattern and relationship with glycemic control and duration of the disease

Methods: It was a longitudinal observational study including 200 patients aged 18 years and older with a confirmed diagnosis of type 1 and type 2 diabetes, admitted in nutrition department A for any reason between 1 August and 31 December 2021.

Results: Among 200 patients with DM, 88(44%) were males and 112(565%) were females. The mean age of the patients was 51.85 ± 18.35 years and mean total duration of diabetes was 11.87 ± 8.9 years. Of them, 135 (67.5%) had one or more dermatoses. The common skin disorders for which patients sought treatment were: xerosis (55.5%), plantar hyperkeratosis (41.3%), onychomycosis (39.2%), and inter-toe intertrigo (18.2%). Risk factors most closely associated with mucocutaneous manifestations included High Blood Pressure (P = 0.000), diabetic peripheral neuropathy (P = 0.018) and obesity or overweight (P = 0.000). But there is no statistically significant relationship with nephropathy (P = 0.14) or retinopathy (P = 0.58).

Conclusion: Skin problems are quite common among diabetic population. Diabetes-related skin lesions can serve as a gateway for microorganisms and possible secondary infections. The early detection of mucocutaneous manifestations in DM is important to be able to avoid and manage the complications and prevent disability.

Volume 81

European Congress of Endocrinology 2022

Milan, Italy
21 May 2022 - 24 May 2022

European Society of Endocrinology 

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