Endocrine Abstracts

Introduction: Hypothyroidism is a frequent endocrinopathy in type 2 diabetes (T2D) which can influence the cardiovascular profile in these patients. Our aim was to study the relationship between hypothyroidism and the occurrence of cardiovascular events in patients with T2D.

Method: It is a retrospective study, including 184 T2D patients, conducted in the department C of the National Institute of Nutrition of Tunis during the year 2021.

Results: The average age of our patients was 61± 10 years, predominantly female 64.1%, with an average duration of diabetes of 14 +/- 8 years. The prevalence of hypothyroidism was 14%. Patients with diabetes and hypothyroidism were mostly female (72%), and more than half of the patients were older than 65 years. These patients had dyslipidemia in 84% of cases. Obesity and metabolic syndrome were present in 64% and 72% of patients respectively. The average body mass index was 31±6 Kg/m². Hypothyroidism was significantly associated with macroangiopathy complications (P = 0.038) mainly coronary artery disease (P = 0.027). A significant association was also notified with renal failure (P = 0.046).

Conclusion: The coexistence of T2D and hypothyroidism predisposes to an increased cardiovascular and renal risk in type 2 diabetic’s patient. This highlights the importance of early detection of this pathology.