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Endocrine Abstracts (2022) 81 EP512 | DOI: 10.1530/endoabs.81.EP512

1INNTA, A, Tunis, Tunisia; 2Faculty of Medicine Of Tunis, A, Tunis, Tunisia; 3University of Tunis El Manar, Nutrition, Tunis, Tunisia


Background: several studies show a ralation between the lack of omega 6 and 3 and the developpement of depression. in other hand, there is a modification in the food behaviors in case of depression which can lead to the persistance of symptoms so the intake of omega 6 and 3 should be assessed for every depressive patient

Methods: 50 patients whith depression were involved in our study. They were recruited from outpatient department in a psychiatric hospital Razi. The severity of depressive symptoms were assessed by HAD and PHQ9. A food history coupled with the frequency of consumption of foods rich in alphalinolenic acid, alphalinoleic acid, eicosapentaenoic acid, docosahexaenoic acid were carried out in order to assess the typical eating habits of patients. Food quantity was estimated using a photographic manual in order to assess food portions and quantification of intakes. The estimate of the daily intakes of EPA (eicosapentaenoic acid), DHA (docosahexaenoic acid) and alpha linolenic acid (GA C18: 3) was made manually based on data from the table of food composition (CIQUAL 2016). We compared the intakes of our poulation compared to the ANCs of the general adult population.

Results: The mea nage of the population is 45 year old. There were 34 women for 16 men. The average BMI was 28.2 Kg/m². The study of consumption shows lipids intake about 36% of total energy intake (TEI). The monounsatured fatty acid about 15.62% of TEI and poly unsatured fatty acid 11.62 % TEI. The intake was unsuffisient for 46% of population for linolenic acid, 86% for EPA, 76% for DHA, 38% for omega 3 and 16% for omega 6. According to HAD more is the intake in omega 3 and linoleic acid less are the severity of symptoms (P=0.03 and 0.002) and according to PHG9 score the depression was more severe if the intake of linoleic acids was low (P=0.04).

Conclusions: the omega 3 and 6 intake are important to assess to improve patient symptoms and ensure faster healing.

Volume 81

European Congress of Endocrinology 2022

Milan, Italy
21 May 2022 - 24 May 2022

European Society of Endocrinology 

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