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Endocrine Abstracts (2022) 81 EP526 | DOI: 10.1530/endoabs.81.EP526

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National Institute of Nutrition of Tunis, Department C, Tunis, Tunisia


Introduction: Insulin therapy remains a treatment of last resort for type 2 diabetic patients with uncontrolled diabetes with oral antidiabetic. The aim of this study was to find a correlation between the initial dose of insulin and the glycated hemoglobin (A1c) level.

Methods: We conducted a cross sectional study. We included 63 patients with type 2 diabetes hospitalized for a switching to insulin in the C department of diabetology and nutrition at the National Nutrition Institute in Tunis, during 3 months. We correlate the initial daily insuline dose and the A1c level using the Spearman test.

Results: The mean age of patients was 58.75± 12 years, 43% were men and 57% were women. The average duration of diabetes was 9,27± 6 years. We found a statistically significant correlation between the initial daily insuline dose and the A1c level (r = 0,66; P = 0.000).

Conclusion: Our results showed a positive correlation between A1c level and initial insulin dose, which encourages us to consider insulin treatment in time to avoid the need for high doses and to minimize side effects.

Volume 81

European Congress of Endocrinology 2022

Milan, Italy
21 May 2022 - 24 May 2022

European Society of Endocrinology 

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