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Endocrine Abstracts (2022) 81 P335 | DOI: 10.1530/endoabs.81.P335

National Institute of Nutrition, Outpatient Department and Functional Explorations, Tunis, Tunisia


Background: Amputation is the major complication of diabetic foot. The aims of our study were to assess prevalence of amputation in a group of long-standing type 1 diabetic patients and to determine its risk factors.

Methods: We conducted a cross-sectional study including type 1 diabetic patients followed at the National Institute of Nutrition of Tunis. All patients had a duration of diabetes ≥ 20 years. Clinical and biological data were collected from medical observation records.

Results: One hundred and fifty five patients with mean age 39.7±9.8 years were included in the study. About 30% of them were male. Age at diagnosis of diabetes was 12.7±7.47 years. Mean duration of diabetes was 27.33±6.38 years. The average of the last four glycated hemglobin (A1c) was 9.45 ±1.62%. The prevalence of amputation was 7.1%. It was associated with low socioeconomic status (P=0.002), low level of education (P=0.045), unemployment (P=0.012), age at diagnosis of diabetes (P=0.039) and anemia (P=0.031).

Conclsion: Amputation is a serious complication of diabetes. It is more associated with socioeconomic factors than with diabetes-related factors.

Volume 81

European Congress of Endocrinology 2022

Milan, Italy
21 May 2022 - 24 May 2022

European Society of Endocrinology 

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