Endocrine Abstracts

A 72 year old lady presented to Endocrinology in 2001 with primary hyperparathyroidism and had a parathyroid adenoma resected, resulting in normocalcaemia. In 2006, she developed mild hypercalcaemia (2.61-2.71 mmol/l) and underwent extensive investigations for recurrent PHPT. Parathyroid localization studies, including FDG PET, failed to identify any adenoma. The patient declined bilateral neck exploration and she was managed conservatively. A DEXA scan showed evidence of oste...

Osteoporosis is estimated to effect more than 3 million people in UK and secondary osteoporosis accounts for about 30% of women and 55% of men with vertebral fractures. There are many causes of secondary osteoporosis, such as endocrine, gastrointestinal disorders, steroid use, as well as immobility, obesity, bulimia and anorexia nervosa. We present a case of Osteoporosis secondary to anorexia nervosa.77 year”s old lady initially referred to bone clinic at the age of 46 wi...

A 72 year old lady was referred after recurrence of fragility fractures, despite being on bisphosphonate therapy for 10 years. She had 2 low-impact falls in 2020 and 2021, which resulted in hip and right distal femur fractures respectively. She had been compliant on alendronic acid 70mg once weekly since 2012, when she was diagnosed with osteoporosis at the age of 62, after sustaining 2 fragility fractures of the distal radius and elbow after separate low-impact falls. DXA sca...