Endocrine Abstracts

Background: Bardet-Biedl syndrome (BBS) is a rare genetic condition characterised by ciliary protein dysfunction leading to multi-organ damage. Patients with BBS can suffer from hyperphagia and severe obesity from childhood and associated weight-related comorbid diseases such as type 2 diabetes and hypertension. However, the optimal weight management strategy and response to weight loss pharmacotherapy is unknown. Case presentation: We present a case of ...

Introduction: Bariatric surgery was shown to treat obesity and decrease cardiovascular risk such as metabolic syndrome, diabetes, and hypertension. In individuals living with HIV, bariatric surgery can alter oral bioavailability of anti-viral therapy through its impact on the intestinal pH, intestinal transit time and first pass mechanism. This can have adverse impact on CD4 count and viral load (VL). Nevertheless, numerous studies highlight that bariatric surgery does not hav...