Endocrine Abstracts

Abstract Unavailable...

Over the last 15 years there has been a revolution in our understanding of how bone and the marrow communicate with other tissues and organs. It is now clear that adipose tissue, brain, the adrenal, the pancreas, and the marrow itself are targets of skeletal mediators. The means of communication are now starting to be delineated. Neural pathways including the sympathetic system and sensory nerves have been delineated. Hormonal function of skeletal peptides has also been deline...

The incidence of diabetes, a disease characterized by high blood glucose levels, is increasing worldwide. Besides the well-known complications of diabetes including cardiovascular disease, retinopathy, nephropathy, and neuropathy, also bone fragility has recently been recognized as a complication of diabetes. In fact, type 1 diabetes is associated with a 6-fold increase in hip fractures with a marked loss of bone mineral density, while type 2 diabetes is associated with a 1.5-...