Searchable abstracts of presentations at key conferences in endocrinology
Previous issue | Volume 90 | ECE2023 | Next issue

25th European Congress of Endocrinology

Istanbul, Turkey
13 May 2023 - 16 May 2023

Card image cap
ECE 2023 will be held in Istanbul, Turkey from 13-16 May 2023. Istanbul is known for its rich culture, historical sites and dynamic nightlife, and we are excited to come together in this city, and look forward to meeting old friends, making new ones, and sharing science, collaborations and ideas.

Oral Communications

Oral Communications 10: Diabetes, Obesity, Metabolism and Nutrition 2

ea0090oc10.1 | Oral Communications 10: Diabetes, Obesity, Metabolism and Nutrition 2 | ECE2023

CRTC2 activates the epithelial-mesenchymal transition of diabetic kidney disease through the CREB-Smad2/3 pathway

Yujie Li , Wang Wenbo

Background: Epithelial-mesenchymal transition (EMT) plays a key role in tubulointerstitial fibrosis, which is a hallmark of diabetic kidney disease (DKD). Our previous studies have shown that CRTC2 can regulate glucose metabolism and lipid metabolism at the same time. However, it is still unclear whether CRTC2 participates in the EMT process of DKD.Methods: We used protein-protein network (PPI) analysis to determine differentially expressed genes in DKD ...

ea0090oc10.2 | Oral Communications 10: Diabetes, Obesity, Metabolism and Nutrition 2 | ECE2023

Characterization of the insulinotropic and glucose lowering actions of hybridized amphibian host defence peptide, tigerinin-1R

Abiodun Falobi Ayodele , Edeani Joy Nneka , Ofosu Wendy Amy , Smyth Lesley , Corcoran Olivia , Dunmore Simon , Ojo Opeolu

Aim: Our previous studies indicated the potential antidiabetic actions of the amphibian host-defence peptide, tigerinin-1. Tigerinin-1R was conjugated with gastric inhibitory polypeptide (GIP) as part of strategies for further development of its therapeutic effects. This study characterises the insulin-releasing and cytotoxic properties of the resulting hybrid peptide.Method: Pure G-TGN was commercially synthesized G-TGN. Insulin releasing effects were a...

ea0090oc10.3 | Oral Communications 10: Diabetes, Obesity, Metabolism and Nutrition 2 | ECE2023

The role of logic learning machine in predicting lipid goal attainment among type 2 diabetes outpatients: Results from the AMD annals study group

Masi Davide , Zilich Rita , Candido Riccardo , Guaita Giacomo , Muselli Marco , Ponzani Paola , Santin Pierluigi , Verda Damiano , Musacchio Nicoletta

Introduction: Lowering low-density lipoprotein cholesterol (LDL-C) via lifestyle change or pharmacologic therapy can reduce the cardiovascular risk (CV) in patients with type 2 diabetes (T2D). However, the response to lipid-lowering interventions is not uniform and a significant proportion of T2D patients do not reach the recommended LDL-C target. Elucidating the factors associated with lipid goal attainment represents an unmet clinical need.Material and...

ea0090oc10.4 | Oral Communications 10: Diabetes, Obesity, Metabolism and Nutrition 2 | ECE2023

Establishing a regional registry for hyperosmolar hyperglycaemic state to share best practice: initial results and future implications

Warmington Emily , Nga Alice Yip Wai , Mounouchos Sophie , Bomphrey Lucy , Dalzell Joseph , Panneerselvam Hari , Webber Jonathan , Dhatariya Khetan , Kempegowda Punith , Group DEKODE Working

Introduction: Hyperosmolar hyperglycaemic state (HHS) is an acute complication of diabetes which requires prompt recognition to prevent morbidity and death. Owing to its low prevalence, clinicians report a lack of confidence in management, which may result in delayed diagnosis and worsened outcomes. The limited literature on HHS management means most guidelines are based solely on expert opinion, resulting in significant discrepancies between care in centres.<p class="abst...

ea0090oc10.5 | Oral Communications 10: Diabetes, Obesity, Metabolism and Nutrition 2 | ECE2023

A study of 512 diabetes-related ketoacidosis episodes shows no added risk or impact on outcomes during Ramadan: Results from DEKODE study

Kempegowda Punith , Rengarajan Lakshmi , Sheikh Haaziq , Soran Vina , Cooper Catherine , Narendran Parth , Hanif Wasim , Karamat Muhammad Ali , Syed Ateeq , Dekode Team

Background: With increasing ethnic diversity in the Western World, it is important to establish the safety of religious practices such as fasting during Ramadan. There is limited information about severity and outcome of diabetes-related ketoacidosis (DKA) during Ramadan outside Middle East.Objective: We studied differences in severity, DKA-related complications and outcomes of DKA before (Shaban), during (Ramadan) and after Ramadan (Shawwal).<p clas...