Searchable abstracts of presentations at key conferences in endocrinology
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25th European Congress of Endocrinology

Istanbul, Turkey
13 May 2023 - 16 May 2023

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ECE 2023 will be held in Istanbul, Turkey from 13-16 May 2023. Istanbul is known for its rich culture, historical sites and dynamic nightlife, and we are excited to come together in this city, and look forward to meeting old friends, making new ones, and sharing science, collaborations and ideas.


GH links to cancer

ea0090s8.1 | GH links to cancer | ECE2023

Abstract unavailable...

ea0090s8.2 | GH links to cancer | ECE2023

Lessons from Laron syndrome

Werner Haim

Laron syndrome (LS) is a rare genetic endocrinopathy that results from mutation or deletion of the growth hormone receptor (GH-R) gene. LS is the best characterized entity under the spectrum of the congenital insulin-like growth factor-1 (IGF1) deficiencies and is typically associated with dwarfism and obesity. Epidemiological studies have shown that LS patients do not develop cancer whereas heterozygous family members have a tumor prevalence similar to the general po...

ea0090s8.3 | GH links to cancer | ECE2023

Lessons from experimental animal models

Kopchick John

Reports dating back to the 1950s have implicated human Growth Hormone (GH) in the initiation and invasive progression of several types of human cancers. A major hurdle in treating cancer is resistance to therapy. Recently, through a series of mechanistic studies using in vitro models and in silico analyses of human cancer patient databases, we have identified a covert role of GH in promoting cancer drug resistance via direct upregulation of: (i) the expression of ATP-...