Endocrine Abstracts

Objectives: To analyze the data of patients seen at the Diabetes and Pregnancy Unit, assessing the frequency of pregnancy planning and whether there are differences in the degree of metabolic control before and during pregnancy, as well as in perinatal outcomes with respect to those who do not plan. All women of childbearing age with Pregestational Diabetes Mellitus(PGDM) should receive preconception counseling to optimize glycemic control, since preconception control is associated with a reduced risk of fetal malformations and perinatal mortality. In addition, pre-existing complications and associated comorbidities should be assessed, as well as the possible use of potentially teratogenic drugs. Despite this, only a minority plan their gestation.

Materials and Methods: Retrospective observational study. Data from 72 patients seen in the Diabetes and Pregnancy Unit, between were collected and analyzed.

Outcomes: Data of 72 women of whom 86.1% were Caucasian, 6.9% Arab, 4.2% Oriental and 2.8% South American, with a mean age of 34.5+/-6.25 years. Regarding the type of PGDM, 64(88.9%) had type 1 DM and 8(11.1%) had type 2 DM, with a mean evolution of 16.34+/-8.56 years since diagnosis. Only 28(38.9%) performed a previous planning, having 26 green light by the Endocrinologist at the time of gestation.

Conclusions: In those patients who do not plan, the initial HbA1c is significantly higher than in those who do plan. An early and close follow-up in the Diabetes and Pregnancy Unit allows improving metabolic control, achieving no significant differences at the end of gestation. No significant differences were observed in terms of perinatal adverse events, however, serious complications such as intrauterine mortality, fetal distress and major malformations occurred in those who do not plan, even though they did not reach statistical significance.