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Endocrine Abstracts (2023) 90 EP1125 | DOI: 10.1530/endoabs.90.EP1125

1National Institute of Nutrition of Tunis, Obesity Research Unit, Bab Saadoun, Tunis, Tunisia, 2National Institute of Nutrition of Tunis, Outpatient Departement and Functional Explorations, Bab Saadoun, Tunis, Tunisia

Introduction: Hyperuricemia is associated with an increased risk of cardiovascular diseases. The aim of this study was to examine the relationship between lipid profile and blood uric acid levels in an adult population with obesity.

Methods: Retrospective study including 200 patients with obesity who consulted the Obesity Unit of the National Institute of Nutrition in Tunis in 2021. Data were collected from patients’ medical records. The lipid profile includes low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglyceride (TG) and total cholesterol (TC). Hyperuricemia was defined as serum uric acid greater than 6 mg/dl (360 µmol/l).

Results: The average age was 47.21±13.88 years with a sexe ratio M/F=0.33. Mean BMI was 41.2 ± 7 kg/m2. Dyslipidemia was found in 55.6% of cases. Hyperuricemia was found in 30.3% of cases. HDL cholesterol was inversely correlated with uric acid levels (r= - 0.2, P0.005). However, there was no significant correlation between TC, LDL, TG and uric acid.

Conclusion: The results of our study showed a strong association between uric acid increase and lipid disorder in patients with obesity. The detection and treatment of these abnormalities will improve the cardiovascular prognosis of patients.

Volume 90

25th European Congress of Endocrinology

Istanbul, Turkey
13 May 2023 - 16 May 2023

European Society of Endocrinology 

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