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Endocrine Abstracts (2023) 90 P801 | DOI: 10.1530/endoabs.90.P801

ECE2023 Poster Presentations Thyroid (163 abstracts)

Prevalence and factors associated with sleep disorders in patients with thyroid cancer

Abdel Mouhaymen Missaoui 1 , Fatma Hamza 2 , Siddiqa Soomauroo 1 , Khawla Ben Ahmed 2 , Wafa Belabed 1 & Mohamed Abid 1

1Hedi Chaker University Hospital, Department of Endocrinology, Sfax, Tunisia; 2Habib Bourguiba University Hospital, Department of Nuclear Medicine, Sfax, Tunisia

Objective: To determine the prevalence and factors associated with sleep disorders in patients with differentiated thyroid cancer (DTC)

Patients and Methods: Analytical cross-sectional study of 39 patients followed for DTC at the Nuclear Medicine Center of Sfax, Tunisia. Sleep disorders were evaluated according to the 7 components of the Pittsburgh Sleep Quality Index (PSQI).

Results: The average age of the patients at the time of the survey was 44.5±13.1 with a female predominance (92.3%). Pathological examination revealed a papillary variant in 89.7%. The response was excellent in 58.9% after a cumulative ablative irradiation of 265.9±197 mCi. Patients had a mean disease-free survival of 4.6±3.4 years. Hormone replacement therapy was chosen in all cases with a mean levothyroxine dose of 2.2±0.4 µg/kg/day. The mean TSH at the time of the survey was 0.48±0.89 mIU/l. These patients sleep on average 06 h an 45 minutes per day. The average sleep time was 41.5±35.4 minutes. The average global PSQI score is high (7.7±3.2 points). The prevalence of sleep disorders was estimated at 66.7%. The PSQI score was not significantly correlated with either the dose of levothyroxine prescribed or the degree of TSH suppression.

Discussion: The prevalence of sleep disturbances affects two out of three patients followed for DTC according to our results. This increased prevalence does not seem to be explained by subclinical hyperthyroidism for therapeutic purposes. Advice on lifestyle management during consultations is desirable to preserve the quality of life of this population.

Volume 90

25th European Congress of Endocrinology

Istanbul, Turkey
13 May 2023 - 16 May 2023

European Society of Endocrinology 

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