Endocrine Abstracts

Introduction: Thyroid cancers in males are rare forms characterized by their aggressiveness and frequent association with locoregional or distant metastases. Objective To describe the clinical and biological characteristics of papillary thyroid carcinomas in male subjects.

Materials and Methods: We conducted a descriptive cross-sectional study involving all male patients followed for papillary thyroid carcinoma at the endocrinology department of Ibn Rochd University Hospital in Casablanca from 1986 to 2023. Univariate statistical analysis was performed for all variables using Excel 2017.

Results: The male gender accounted for 45 patients, representing a prevalence of 4.4%. The mean age was 50 years, with a history of familial thyroid neoplasia in 6.6% of cases. The most common presenting complaint was multi-heteronodular goiter in 45% of cases. The average tumor size was (0.2–6.2 cm). All patients underwent total thyroidectomy, with lymph node dissection performed in 20% of cases. Radioiodine therapy was indicated in 59% of patients. Papillary carcinoma was the histological type in all cases, classified as high risk in 51.4% of cases. Follow-up revealed 25% locoregional recurrences and distant metastasis (pulmonary) in 5% of patients. Prognosis was significantly correlated with tumor size and locoregional or distant metastases at the time of diagnosis.

Discussion: Thyroid cancers in male subjects are rare and aggressive forms. Their major prognostic impact influences subsequent management, as reported in the literature.