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Endocrine Abstracts (2024) 99 EP355 | DOI: 10.1530/endoabs.99.EP355

1University General Hospital of Heraklion, Endocrinology and Diabetes Clinic, Crete, Greece; 2University of Crete, Department of Social Medicine, Heraklion, Crete, Greece; 3University General Hospital of Heraklion, Department of Vascular Surgery, Crete, Greece; 4University General Hospital of Heraklion, Department of Dermatology, Crete, Greece; 5Cambridgeshire & Peterborough NHS Foundation Trust, Cambridge, United Kingdom


Background: Psychological distress is elevated during pandemics such as the COVID-19 outbreak. Patients with diabetes mellitus (DM), are a particularly vulnerable risk group. However, data of the impact of other endocrinopathies on psychological status of patients during pandemics are lacking so far.

Aim: To compare psychological distress about COVID-19 pandemic, between endocrine patients with a variety of endocrinopathies and patients with non-endocrine diseases (controls) seen in the outpatient clinics of the University Hospital, Heraklion, Crete, Greece.

Methods: One hundred and seventy four endocrine patients seen at the outpatient Endocrine clinic and two hundred and four controls without endocrinopathies seen at the Dermatology and Vascular Surgery outpatient clinics completed questionnaires about demographics, need for information, sources of information worries about the COVID-19 pandemic and the Greek version of the DASS-21 for psychological distress questionnaire. The levels and prevalence of stress, anxiety, and depression about the COVID-19 pandemic between the two groups were compared after controlling for age, gender, education, residence, employment status and ever diagnosed with psychiatric disease in multiple logistic regression models. Ethical approval was obtained by Institutional Review Board.

Results: Mean age of endocrine patients was 50.8 years and controls 45.7 years (P<0.001); with predominance of women in both groups (P=0.017). Among endocrine patients 62.1% suffered from thyroid diseases, 29.9% from DM, 18.9% from gonadal dysfunction and 12.1% from pituitary disorders. Adrenal and calcium disorders were mentioned in less than 10% of patients. The majority of endocrine patients (83.1%) were well-controlled, whereas 28.7% had two or more endocrinopathies. Hypertension and coronary vascular disease were more common in endocrine patients compared to controls (28.7% vs 16.2% and 8.7% vs 3.4% respectively), Mild and moderate stress symptoms were observed in both groups. Patients with two or more endocrinopathies reported significantly increased prevalence of stress symptoms compared to controls (odds ratio (OR): 2, 1; P=0, 045). We found no differences in anxiety and depression symptoms between the two groups, which showed low rates of both.

Conclusions: The current study highlights the increased risk of stress symptoms in endocrine patients with two or more endocrinopathies during Covid-19 pandemic. These results are relevant when designing policies on information on pandemics and supportive measures for endocrine patients in General Hospitals.

Volume 99

26th European Congress of Endocrinology

Stockholm, Sweden
11 May 2024 - 14 May 2024

European Society of Endocrinology 

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