Applicability of intermittent intersticial glucose monitoring in patients admitted to the intensive care unit of the hospital universitario san cecilio in granada

Juarez Raul Rodriguez; Carmen Andreo-Lopez Maria Del; Silla Elena Martinez; Sanchez Javier Garcia; Noguera Laura Canovas; Delgado Montoya Juan Luis; Cruces Moreno Maria Teresa; Lopez-Ibarra Lozano Pablo Jose

doi:10.1530/endoabs.99.EP491

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Endocrine Abstracts (2024) 99 EP491 | DOI: 10.1530/endoabs.99.EP491

ECE2024 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (383 abstracts)

Applicability of intermittent intersticial glucose monitoring in patients admitted to the intensive care unit of the hospital universitario san cecilio in granada

Raúl Rodríguez Juárez ¹ , María Del Carmen Andreo-Lopez ¹ , Elena Martínez Silla ¹ , Javier García Sánchez ¹ , Laura Cánovas Noguera ¹ , Juan Luis Delgado Montoya ¹ , Maria Teresa Cruces Moreno ² & Pablo José López-Ibarra Lozano ¹

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¹Granada, UCG Endocrinología y Nutrición, Granada, Spain; ²Granada, UCG Cuidados Intensivos, Granada, Spain

Objective: Optimal glycemic management in critically ill patients with diabetes or stress hyperglycemia has prognostic value. For adjustment, the most used measurement in the Intensive Care Unit (ICU) is the capillary glucose. In this study, we compare intersticial glucose (IG) and capillary glucose (CG) concentrations to assess the applicability of sensor placement in patients requiring vasoactive agents.

Materials and Methods: Prospective longitudinal observational study with 6 diabetic patients or stress hyperglycemia admitted to the ICU. Demographic (sex, age), clinical (DM, high blood pressure, obesity), hemodynamic (need for vasoactives) and metabolic (A1c-type glycosylated hemoglobin (HbA1c) determined by laboratory analysis, presence of angiopathic complications, CG and IGM measurements (in mg/dl)) variables were collected. The statistical analysis was performed with the IBM SPSS v.25 programme (Statistical significance P<0.05).

Results: 67% were males with a mean age of 65.5±21.5 years. 100% have high blood pressure and 50% obese. 67% were type 2 diabetic with a mean HbA1c 6.5±1.6% and 75% had angiopathic complications. The mean CG was 205±66.9 and the mean IG was 152.2±53.4. 67% required vasoactive agents. There was a positive correlation between capillary and interstitial measurements both in patients with and without vasoactive agents (r=0.8 and r=0.7, respectively, P=0.0).

Conclusions: There’s a positive and strong correlation between capillary and interstitial measurements, with or without vasoactive agents. This suggests that, regardless of the patient’s hemodynamic situation, IG could be useful as a glycemic measurement instrument in critically ill patients, thus improving their comfort.