Impact of polycystic ovary syndrome on health related quality of life in correlation with marital status: a multinational cross-sectional study

Elleuch Mouna; Elloumi Yesmine; Dhoha Ben Salah; Boujelben Khouloud; Krichen Zeineb; Ellouze Roua; Mnif Fatma; Mnif Mouna; Charfi Nadia; Faten Hadj Kacem; Abid Mohamed; Mejdoub Nabila

doi:10.1530/endoabs.99.EP643

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Endocrine Abstracts (2024) 99 EP643 | DOI: 10.1530/endoabs.99.EP643

ECE2024 Eposter Presentations Reproductive and Developmental Endocrinology (78 abstracts)

Impact of polycystic ovary syndrome on health related quality of life in correlation with marital status: a multinational cross-sectional study

Elleuch Mouna ¹ , Elloumi Yesmine ¹ , Ben Salah Dhoha ¹ , Boujelben Khouloud ¹ , Krichen Zeineb ¹ , Ellouze Roua ¹ , Mnif Fatma ¹ , Mnif Mouna ¹ , Charfi Nadia ¹ , Hadj Kacem Faten ¹ , Abid Mohamed ¹ & Mejdoub Nabila ¹

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¹Hospital of Hedi Chaker

Background and Aims: The Rotterdam criteria are the most accepted criteria for the diagnosis of polycystic ovary syndrome (PCOS). The aim of this research work is to study the quality of life of Tunisian and French women with PCOS according to their marital status.

Methods: A cross-sectional study involved 172 women with PCOS. Data collection was based on telephone interviews with tunisian patients who were diagnosed with PCOS based on rotterdam criteria and french patients via Google Forms over an international group specifically for women with PCOS. A quality-of-life questionnaire specific to polycystic ovary syndrome that exists in two forms. PCOSQ-42 for single women and PCOSQ-47 for married women. Both of them have 5 domains. The responses are rank-transformed and presented as scores.

Results: The mean age of tunisian patients was 28±5.9 years while the mean age of french patients was 26.39±4.3 years. 44 tunisian patients were married and 44 french patients were married. The study of HRQoL by domain had shown that the domain of menstrual disorders and fertility was the most affected in single women indicating a low mean score (2.84±0,8). Whereas the adaptation domain reported the highest mean score (3.38±0.8). Married women’s quality of life was more impaired than single women’s: 48.31% had marked impairment of HRQoL and 39.33% had marginal or moderate impairment of HRQoL. The lowest mean score was in the psychological and emotional state domain (2.86±0.7). The highest mean score was in the fertility and sex life domain (3.26±0.9). So this was the domain with the least impairment.

Conclusions: PCOS contributes to an overall diminished HRQo. These results may have implications for the clinical practice and suggest the need for specific interventions in women with PCOS.