Endocrine Abstracts

JOINT3740

Introduction and Objective: The transition of adolescents with Type 1 Diabetes Mellitus (T1DM) to adult Endocrinology services coincides with significant personal changes. Interstitial glucose monitoring is a key tool for diabetes management. This study aims to evaluate metabolic control in adolescents after transitioning to adult endocrinology follow-up.

Materials and Methods: A descriptive observational study was conducted on patients aged 14–18 years who had at least one data download in 2024 while under follow-up at the General Endocrinology outpatient clinic of Hospital Universitario Clínico San Cecilio (Granada). Anthropometric variables, treatment characteristics, and disease control parameters (glucometry and HbA1c) were analyzed. Statistical analysis was performed using SPSS v.15.

Results: A total of 35 patients with T1DM were included, 54.3% male, with a mean age of 16.2 ± 1.4 years. All were on basal-bolus insulin therapy (1 ± 0.4 U/kg), with a mean disease duration of 7 ± 4.2 years. The mean follow-up period was 9.7 ± 8.2 months. Mean BMI was 22 ± 3.4 kg/m², and mean HbA1c was 7.9 ± 1.6%. The average insulin sensitivity factor was 33 ± 20.6. The mean time in range (TIR) was 51%, time above range (TAR) 44%, and time below range (TBR) 5%. The mean coefficient of variation was 40.2 ± 7.5%, with a Glucose Management Indicator (GMI) of 7.5 ± 1%. The mean number of daily sensor readings was 10 ± 2, with an average sensor activity rate of 76 ± 20%. Three patients experienced one or more episodes of severe diabetic ketoacidosis requiring hospitalization and intensive care unit (ICU) admission since starting follow-up.

Conclusions: This study highlights suboptimal metabolic control in T1DM patients transitioning from pediatric to adult care. The creation of specialized transition units could improve metabolic outcomes and prevent complications in this population.