ECEESPE2025 ePoster Presentations Pituitary, Neuroendocrinology and Puberty (220 abstracts)
Usefulness of serial prolactin measurement to confirm the presence of hyperprolactinemia
Raúl Rodríguez Juárez 1 , Elena Martínez Silla 1 , Laura Cánovas Noguera 1 , Juan Luis Delgado Montoya 1 , Nuria Birruezo Hernández 1 , Yael Giner Esteban 1 , Maria Dolores Aviles Perez 1 , Torralbo Martín 1 & Pablo J López- Ibarra Lozano 1
1Hospital Universitario Clínico San Cecilio, Granada, Spain.
JOINT2449
Introduction: Hyperprolactinemia is a frequent cause of referral to endocrinology outpatient clinics, which is due to many causes (physiological, pharmacological, pathological). Once some have been excluded, many studies recommend performing a serial prolactin measurement to rule out stress hyperprolactinemia, although it isn’t standardised. Objective: to evaluate the usefulness of serial prolactin measurement to confirm hyperprolactinemia diagnosis.
Materials and Methods: Descriptive study of 60 patients who underwent serial prolactin measurements between the years 2023-24 in follow-up in our clinics. Demographic (sex, age) and analytical (basal prolactin, at 20 and 40 minutes) variables were collected. Regarding the measurement, a peripheral intravenous line was inserted and a baseline, at 20 and at 40 minutes value was taken. It was established that prolactin was elevated above 20 (men) or 25 (women). The statistical analysis was performed with the IBM SPSS v.25 programme (Statistical significance P <0.05).
Results: 60 patients were analysed, 80% women with a mean age of 31.1 ± 14.7 years. 66.7% and 70% showed normal prolactin values at 20 and 40 minutes, respectively. Basal and 20-minute prolactin and basal and 40-minute prolactin means difference were 4 ± 7.1 and 6.5 ± 10.8, with a statistical significance of 0.01 in both.
Conclusions: In most patients, prolactin levels become normal after 20 and 40 minutes of sampling, after removing other confounding factors that may lead to stress hyperprolactinemia. A statistically significant difference is also observed between baseline, at 20 and at 40 minutes values. This demonstrates the usefulness of the measurement to rule out stress hyperprolactinemia, as well as to avoid redundant complementary tests and avoid unnecessary worries for the patient.
Volume 110
Article tools
My recent searches
My recently viewed abstracts
Authors
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2025 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more