ECEESPE2025 ePoster Presentations Diabetes and Insulin (245 abstracts)
Impact of surgical interventions on glycemic control in hospitalized diabetic patients
Mohamed Khairi Arous 1 , Houcem Elomma Mrabet 2 , Mouna Mnif 1 , Hamdi Frikha 1 , Mariam Akacka 2 , Najoua Lassoued 2 , Zantour Baha 2 , Mohamed Abid 1 , Mouna Elleuch 1 , Alaya Wafa 2 & Nabila Rekik Majdoub 1
1Hedi Chaker University Hospital, Department of Endocrinology, Sfax, Tunisia; 2University Hospital Tahar Sfar, Department of Endocrinology, Mahdia, Tunisia
JOINT723
Introduction: Surgical interventions are high-risk situations for diabetic patients due to the metabolic disturbances induced by surgical stress and the resulting hormonal changes. These disturbances and sometimes inadequate therapeutic adjustments can impair glycemic control and increase the risk of acute complications. Despite its clinical significance, few studies have explored the impact of surgical interventions on the glycemic control of hospitalized diabetic patients. This study aims to assess the repercussions of surgical interventions on glycemic control.
Patients and methods: This multicenter cross-sectional study was conducted between February and March 2024 in three Tunisian university hospital centers: Hedi Chaker and Habib Bourguiba University Hospitals in Sfax, and Taher Sfar University Hospital in Mahdia. The study included diabetic patients hospitalized in medical and surgical departments. The collected data included the reason for admission, whether a surgical intervention was performed during hospitalization, the occurrence of acute hyperglycemic decompensation or hypoglycemia, and the assessment of glycemic control. Glycemic control was considered insufficient if less than 50% of measured capillary blood glucose levels (CBG) were below the intra-hospital target range (defined by the ADA between 1 and 1.8 g/l), moderate if 50 to 70% of CBG values were within the target range, and satisfactory if more than 70% of CBG values achieved this target.
Results: Among the 315 patients included, 102 (32%) underwent surgical intervention during their hospitalization. Diabetes was newly diagnosed in one patient following surgery. Acute hyperglycemic decompensation occurred in 21 patients (20.6%), while hypoglycemia was observed in 23 patients (22.5%). Poor glycemic control was noted in 41 patients (40.2%), and glycemic monitoring was not performed in 17 patients (16.7%). Insulin therapy was discontinued in 21 of the 49 insulin-treated patients who underwent surgery. Surgical interventions were not significantly associated with acute hyperglycemic decompensation (P = 0.519) or hypoglycemia (P = 0.434). Similarly, surgical interventions were not significantly associated with poor glycemic control (P = 0.585).
Conclusion: Contrary to expectations, surgical interventions were not systematically associated with acute decompensations or poor glycemic control in hospitalized diabetic patients. However, this study highlights the importance of optimized perioperative management to maintain adequate glycemic control and prevent associated complications.
Volume 110
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Endocrine Abstracts
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