Endocrine Abstracts

JOINT1289

Background: Hepatic glycogenosis is the liver response to poor glycemic control in type 1 diabetes mellitus The rarity of the glycogenic hepatopathy in children leads to misdiagnosis. In this case report, we highlighted the identification of key clinical symptoms, of HG, in order to prevent HG from continuing to be misdiagnosed, and to ensure prompt management.

Case presentation: A twelve years old boy who was diagnosed one year earlier to his presentation to ED with abdominal pain. His Growth percentiles were below 3rd centile for the weight and on the 20th centile for the height. His abdominal examinationshowed tenderness in the right lower quadrant of the abdomen with hepatomegaly of 8 cm below the costal margin. The laboratory investigationsrevealed a very high HbA1C of 15.0 %, elevated liver enzymes and negative CMV and EBV serology, and other infectious causes of hepatomegaly. Ultrasound abdomenreported an Enlarged liver, measuring 17.9 cm with coarse parenchyma, but no sizeable focal mass lesion.

Conclusion: Although rare complication, of poorly glycemic control of type 1 Diabetes mellitus in children, hepatic glycogenosis, a temporary finding these patient which improves with glycemic control of children with T1DM. We report this case to raise attention of physicians to such complication, as it should not be misdiagnosed and for the prompt and early management of these patients.