Endocrine Abstracts

JOINT1435

Today, diabetes mellitus is a major public health problem. Type 2 diabetes is the most common form, accounting for around 90% of all forms of diabetes. The ever-increasing frequency of this condition may be explained by lifestyle changes, particularly sedentary lifestyles, high-fat diets, obesity and an ageing population. The seriousness of this condition is linked to the occurrence of metabolic, infectious and degenerative complications, including renal manifestations. The aim of our work was to determine the distribution of diabetes according to sex, age and renal complications, and to study certain biochemical parameters of the glycemic and renal balance of people with diabetes and/or diabetic nephropathy (n= 65). We found that the risk of diabetic nephropathy was higher in women than in men, and that 11% developed renal complications. 86% had above-normal fasting blood glucose levels, and blood glucose levels were higher in those with ND (2.52±0.95 g/l) than in patients without ND (1.92±0.72 g/l). 85% of patients had HBA1c values above threshold, and mean HBA1c was higher in those with ND (9.2±2.24%) than in those without ND (8.28±1.60%). In addition, 47% had hypercreatininemia, of whom 11% had ND and 7% had hypocreatinemia. Hyper-uremia was present in 56% of patients, of whom 15% had ND, and 45% of patients had hyper-uricemia, of whom 10% had ND. It also appeared from our results that renal workup is effective in estimating function as well as the degree of renal complication.

Key words: Diabetes, nephropathy, glycemia, HBA1c, creatinemia, uremia, uricemia.