IES2025 Research, Audit and Quality Improvement Projects E-Posters (60 abstracts)
Unrecognised diabetes mellitus in acute stroke: prevalence and impact on hospital outcomes
Hafiz Muhammad Sohail 1 , Devin Mc Cabe 1 , Orla Kennedy 1 , Julieanne Kirwan 1 , Keneilwe Malomo 2 , Sarah Al Azawei 3 , Joseph A. Harbison 1,4 & Ontefetse Ntlholang 1,3,4
1Acute stroke services, St James’s Hospital, Dublin 8, Ireland; 2Department of Medicine for the Older Person, Mater Misericordae University and St Mary’s Hospital, Dublin, Ireland; 3Acute and General Medicine, MED Directorate, St James’s Hospital, Dublin 8, Ireland; 4Discipline of Medical Gerontology, School of Medicine, Trinity College Dublin, Dublin 2, Ireland
Background: Diabetes mellitus (DM) is common in acute stroke patients and may influence treatment and recovery. This study assessed the frequency of newly diagnosed DM in stroke admissions over two years and examined whether DM status (new, known, or absent) affected patient characteristics, hospital length of stay (LOS), and in-hospital mortality.
Methods: We retrospectively reviewed 528 consecutive stroke admissions. Patients were categorised as having newly diagnosed DM, known DM, or no DM.Group differences were analysed using non-parametric and categorical tests. Multinomial logistic regression identified factors associated with DM status. Predictors of mortality and LOS were assessed using binary logistic and multiple linear regression, respectively, adjusting for relevant covariates. Significance was set at P < 0.05 (SPSS v 22).
Results: Of 528 patients, 8.1% had newly diagnosed DM, 28.0% had known DM, 63.8% had no DM. Known DM was associated with lower eGFR (median 60 vs. 73, P < 0.001), higher glucose , HbA1c and more ketone positivity. Multinomial regression showed known DM was linked to lower eGFR (aOR 0.979, P < 0.001) and fewer prior strokes/TIAs (aOR 0.65, P = 0.040). Newly diagnosed DM had no unique predictors. Mortality was associated with older age and absence of prior stroke/TIA but not with DM status. LOS was longer with ischaemic heart disease (8.8%, P = 0.033) and when DM coexisted with atrial fibrillation(8.2%, P = 0.023).
Conclusion: Nearly 1 in 12 stroke patients had newly diagnosed DM. While DM status alone didn’t impact mortality or LOS, comorbidities did, supporting routine DM screening and integrated stroke care.
Volume 115
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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