Endocrine Abstracts

Parathyroid UK is a national patient organisation committed to improving the quality of life for everyone with parathyroid disorders. We provide information and support to empower our 5,000 members affected by a parathyroid condition to become active in the management of their condition. In Primary Hyperparathyroidism too much parathyroid hormone is produced by one or more enlarged or overactive parathyroid glands, causing hypercalcaemia. This impairs quality of life and incre...

IntroductionSubacute thyroiditis is a rare cause of thyrotoxicosis arising in the context or following viral infections. This disorder is more frequent in women than in men (male/female ratio of 1:4). In addition to respiratory symptoms, the SARS-CoV-2 infection (COVID-19) has been associated with extrapulmonary manifestations. Herein we report a male patient with hyperthyroid symptoms starting four-week after a positive test for COVID-19.<p class="a...

Thyroid hormone (TH) is one of the key players in modulating cardiovascular function. The hormone increases heart rate and force of contraction by modulating cardiac gene expression, thereby providing a molecular explanation for the clinical correlation between hyperthyroidism and cardiovascular mortality. The talk will present current aspects of cardiovascular function mediated by newly discovered TH metabolites. Recent studies have shown that a single injection of 3-iodo-<sm...

Most cases of gynecomastia are idiopathic. Among the most frequently identified etiologies are: persistent pubertal gynecomastia, hypogonadism, anabolic steroids and other pharmaceutical drugs use. In the literature, ginecomastia is a well-recognized manifestation of thyrotoxicosis in male patients (in the range of 10% to 40%). However, it is extremely rare in clinical practice as the initial presentation of thyrotoxicosis. The two main factors that contribute to gynecomastia ...

Background: Management of PHPT includes successful localization of parathyroid adenoma(s) by nuclear imaging and ultrasound scans allowing focused or minimally invasive surgery. Our aim was to assess the accuracy of parathyroid imaging in surgically-treated patients with primary hyperparathyroidism (PHPT) by correlating the imaging findings with surgical findings and cure of hyperparathyroidism. We also compared the surgical outcomes in patients with con...

Background: Management of PHPT includes successful localization of parathyroid adenoma(s) by nuclear imaging and ultrasound scans allowing focused or minimally invasive surgery. Our aim was to assess the accuracy of parathyroid imaging in surgically-treated patients with primary hyperparathyroidism (PHPT) by correlating the imaging findings with surgical findings and cure of hyperparathyroidism. We also compared the surgical outcomes in patients with con...

Introduction: Hypercalcemia is one of the most common endocrine disorders. Most out-patients’s cases are due to primary hyperparathyroidism and run with chronic and low-moderate hypercalcemia. We report a case of acute and severe hipercalcemia of unknown origin. Diagnostic procedure is discussed.Case report: A 53-year-old man was admitted to the Intensive Care Unit due to progressive deterioration of consciousness in the last 48 hours, associating r...

Introduction: Data from several clinical trials have shown positive effects of GLP1 analogue drugs on renal function in patients with type 2 diabetes (T2DM). However, there are very few reported results on its potential renoprotective effect in routine clinical practice. Our aim is to evaluate the effects of the addition of weekly dulaglutide (a GLP-1 analogue) to the normoglycemic treatment of patients with T2DM on renal function in a real-world cohort of patients.<p clas...

Introduction: Sodium glucose cotransporter 2 inhibitors (SGT2-i) and glucagon-like peptide-1 receptor agonists (GLP-1-ra) conform two families of drugs with beneficial effects on weight and glycemia. Our aim is to identify epidemiological and clinical characteristics of patients, candidates to receive one of these classes of drugs, that can influence on physician’s decisions.Methods/design: Retrospective observational research. Data from patients wi...

Introduction: In contrast to general population, clinical consequences related to low levels of 25-hydroxyvitamin D in HIV-infected patients with overweight are not established. The aim of our study was to investigate the influence of weight on clinical parameters and on calcium-phosphorus homeostasis in HIV-patients with vitamin D deficiency.Methods/design: Prospective study of HIV outpatients treated in our hospital. Vitamin D deficiency (D-DEF) was de...