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ea0090p127 | Environmental Endocrinology | ECE2023

Assessment of oxidative stress, neurotoxicity, genotoxicity and prey-predator interactions in freshwater snails exposed to microplastics

Microplastics are one of the major pollutants over the globe jeopardising the health of aquatic life. The ecotoxicological effects of microplastics are well investigated in marine organisms, however, their impact on freshwater ecosystem remain unnoticed. Gastropod molluscs serve as good bioindicators for environmental toxicology. Therefore, we studied two commonly found freshwater snails, Lymnaea acuminata and Indoplanorbis exustus and checked the effect of m...

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ea0099p471 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Subgroup analysis of phase 3 study of fixed-dose combination of dapagliflozin, glimepiride and metformin IR in type 2 diabetes mellitus patients with HbA1c 9%-11%

Kurmi Prakash , Singh Manish , Gupta Vishal , Siddegowda Chikkalingaiah , Shukla Jitendra , Gofne Sandip , Lomte Nilesh , Shendkar Kaustubh , Gangwani Dinesh , Kumar Surendra , Gupta Sandeep , G Nagarajaiah Aravind , Bhaskar Amit , Sharma Prabhat , Baidya Arjun , Maiti Animesh , Gowda Ambana , Ambaliya Jayesh , Giriappa K Balachandra , Mahavar Sunil , Gupta Hemant , Mandodari Rajurkar Dr , Sonowal Supriya , Patel Piyush , Patil Dipak , Lakhwani Lalit , Ghadge Pravin , Mehta Suyog , Joglekar Sadhna

Background and Objective: Fixed-dose combination (FDC) of dapagliflozin+metformin+sulfonylurea with complementary mechanisms can provide effective glycaemic control, preserve beta-cell function, improved compliance without risk of weight gain, and reno-protective action in type 2 diabetes mellitus (T2DM) patients. This subgroup analysis aimed to assess efficacy and safety of triple-drug FDC versus (vs) two-drug combination in T2DM Indian patients with HbA1c 9%-11%.<p class...

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ea0099ep337 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Subgroup analysis of phase 3 study of fixed-dose combination of dapagliflozin, glimepiride and metformin IR in type 2 diabetes mellitus patients aged <45 years and 45 to 65 years

Kurmi Prakash , Singh Manish , Gupta Vishal , Siddegowda Chikkalingaiah , Shukla Jitendra , Gofne Sandip , Lomte Nilesh , Shendkar Kaustubh , Gangwani Dinesh , Kumar Surendra , Gupta Sandeep , G Nagarajaiah Aravind , Bhaskar Amit , Sharma Prabhat , Baidya Arjun , Maiti Animesh , Gowda Ambana , Ambaliya Jayesh , Giriappa K Balachandra , Mahavar Sunil , Gupta Hemant , Rajurkar Mandodari , Sonowal Supriya , Patel Piyush , Patil Dipak , Lakhwani Lalit , Ghadge Pravin , Mehta Suyog , Joglekar Sadhna

Background and Objective: Fixed-dose combination (FDC) of dapagliflozin+metformin+sulfonylurea with complementary mechanisms can provide effective glycaemic control, preserve beta-cell function, improved compliance without risk of weight gain, and reno-protective action in type 2 diabetes mellitus (T2DM) patients. This subgroup analysis assessed efficacy and safety of triple-drug FDC vs (vs) two-drug combination in T2DM Indian patients aged <45 years and 45-65 years.<p...

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Endocrine Abstracts

Assessment of oxidative stress, neurotoxicity, genotoxicity and prey-predator interactions in freshwater snails exposed to microplastics

Subgroup analysis of phase 3 study of fixed-dose combination of dapagliflozin, glimepiride and metformin IR in type 2 diabetes mellitus patients with HbA1c 9%-11%

Subgroup analysis of phase 3 study of fixed-dose combination of dapagliflozin, glimepiride and metformin IR in type 2 diabetes mellitus patients aged <45 years and 45 to 65 years

BiosciAbstracts