Endocrine Abstracts

Introduction: Differentiated thyroid cancer accounts for 1.5% of all pediatric malignancies. Papillary thyroid cancer (PTC) is the most common subtype and is associated with more advanced disease at diagnosis compared to adults. The aim of this study was to identify long-term outcomes of pediatric PTC.Methods: Records of 30 patients with PTC diagnosed in childhood and adolescence and followed up at Istanbul Faculty of Medicine were reviewed retrospective...

Thyrotoxicosis and primary hyperaldosteronism both cause hypokalemic periodic paralysis. A 51-year-old woman, with a history of 3 episodes of transient muscle weakness, was admitted to the emergency unit with complaint of the weakness of legs. Her medical history included hypertension for 10 years. A nodule approximately 3 cm in diameter was palpated in the left anterior neck. Decreased strength (2/5) and deep tendon reflexes in lower extremities symmetrically with normal sens...

Introduction: To assess the demographic data, etiological distribution, methods of diagnosis in patients with clinical (CS) and subclinical Cushing’s (SCC) syndrome.Methods: Forty-seven patients, 35 with CS and 12 with SCC patients were evaluated retrospectively.Results: Of the 35 patients with CS, 55% were classified as ACTH-dependent and 43% as ACTH-independent. Pituitary adenoma constituted 54% of cases, adrenal adenoma 34%...

Introduction: The prevalence of primary adrenal insufficiency (Addison disease; AD) in pregnancy is unknown. Female patients with adrenal insufficiency are usually infertile and once get pregnant are at increased risk for preterm deliveries, Cesarean section and babies with low birth weights. Recognition of AD during pregnancy may be difficult as many of the clinical complaints like weakness, lightheadness, syncope, nausea, vomiting, hyponatremia, and increased pigmentation ca...

Introduction: Manifestations of MEN2B include medullary carcinoma of thyroid (MCT), pheochromocytoma, and a number of somatic mutations like marfanoid habitus, mucosal neuromas, ganglioneuromatosis of the bowel. Dural ectasia results from enlargement of the spinal canal, was identified in 63–92% of patients with Marfan syndrome, however, it was not previously described in MEN2B. We detected dural ectasia in our patient with MEN2B.Case report: A 28 y...

Introduction: Celiac disease (CD) is gluten sensitive enteropathy with a wide spectrum of severity. Iron deficiency, growth retardation, shortness, delayed puberty can be seen. Osteomalacia and hypocalcemia are results of malabsorbtion of vitamin D and calcium which may cause secondary hyperparathyroidism. In untreated cases for a long period, tertiary hyperparathyroidism can also be seen due to autonomy of parathyroid glands with chronic stimulation. There are some cases of p...

Introduction: Steroid 11β-hydroxylase deficiency is a relatively rare form of congenital adrenal hyperplasia characterized by the overproduction of adrenal androgens and deoxycorticosterone. It usually presents with virilization of the female fetus, precocious puberty in male infants and hypertension with or without hypokalemia in both genders. Because of high levels of mineralocorticoids, patients rarely present with Addisonian crisis. We describe a male patient with 11&...

Plant growth factors are used commonly in agriculture. The effect of these factors on human health is unknown. Gibberellins are the most commonly used growth factors that have the structure of Diterpenoid acid. One of the gibberellins (GA3) induces tumor formation in mice but the mechanism of action is not known. We here examined changes in levels of GH and IGF-1 and examined whether there is a correlation between growth factors’ levels and weight changes.<p class="ab...

Introduction: Many factors influence intensity and duration of exposure to ultraviolet, including geographic location, season, dietary intake, atmospheric conditions and the daily sunlight exposure. Study was performed to determine prevelance of hypovitaminosis in housebound elderly.Design: 41 people (22 men and 19 women) living in Konya Residantal Care (RC) were taken. Serum 25-OH vitamin D (VD) measured in winter and in summer. Results were evaluated b...

Introduction: The diagnosis of an increasing number of adrenal tumors, so-called ‘incidentalomas’, is the result of technological advances in imaging such as abdominal ultrasonography (USG), computed tomography (CT) and magnetic resonance imaging (MRI). We present a case of an accessory spleen mimicking a nonfunctional incidentaloma.Case: An 18-year-old boy was referred for evaluating of left adrenal mass that was detected by USG performed for ...