Endocrine Abstracts

Background: Acromegaly is a rare endocrine disorder due to growth hormone excess attributed to a pituitary tumor, in most cases. Epidemiological data of acromegaly are derived from national tumor registries or population studies while there are no published data in the Greek population except for a few small studies regarding treatment outcome.Methods: We carried out a retrospective ongoing observational study to determine the epidemiology, presentation ...

Acromegaly is a rare and insidious endocrine disease, with increased morbidity and mortality mainly due to delayed diagnosis and inadequate control. There are many population studies assessing the epidemiology of acromegaly in Europe while in Greece, there are no published data except for a few small studies regarding treatment outcome.Aim: To determine the epidemiology, presentation and outcome in patients with acromegaly in Crete, Greece.<p class="...

Introduction: Allogeneic bone marrow transplantation (BMT) represents the only effective approach to the cure of thalassemia major, offering high rates of success especially in a pediatric setting. Endocrine complications are expected in these patients due to both primary disease and BMT process. Iron overload, desferrioxamine treatment, cytotoxic agents used in the preparative regimen, and posttransplant immunosuppression period contribute to various endocrine disorders.<...

Although vaspin is regarded an insulin-sensitizing adipokine, its role in gestational diabetes mellitus (GDM) is currently unknown. We aimed to evaluate serum vaspin levels and their correlation with insulin resistance in women with and without GDM. Forty-four women with GDM (GDM Group 20 managed with diet only (GDM-diet) and 24 with diet plus insulin (GDM-insulin)) and 44 age-matched pregnant women with normal glucose tolerance (control group) were studied. Serum glucose, lip...

Background: Primary hyperparathyroidism (PHPT) has been linked to glucose homeostasis disorders, leading to insulin resistance and type 2 diabetes mellitus. Previous small studies evaluating the effect of parathyroidectomy (PTX) on various parameters of glucose metabolism have produced conflicting results. The impact of PTX on incretin hormone levels has not been studied yet. The aim of this pilot study was to investigate the effect of PTX on markers of glucose metabolism and ...